Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567091 | 1.00 | LMNA (0.49) | LMNAAKT1TAAR1TSHRCYP3A4 | |
| SCHEMBL15239316 | 0.86 | TAAR1 (0.41) | LMNAAKT1TAAR1TSHRMAOA | |
| SCHEMBL2610008 | 0.82 | LMNA (0.54) | LMNAAKT1TAAR1TSHRCTSL | |
| SCHEMBL2181334 | 0.82 | LMNA (0.54) | LMNAAKT1TAAR1TSHRCTSL | |
| SCHEMBL5501059 | 0.80 | CTRB1 (0.42) | TAAR1TSHRMAOBHTT | |
| SCHEMBL12537283 | 0.78 | LMNA (0.50) | LMNAAKT1TAAR1TSHRCTSL | |
| SCHEMBL567327 | 0.78 | GLA (0.47) | CDC25B | |
| SCHEMBL536617 | 0.78 | GLA (0.47) | CDC25B | |
| SCHEMBL7259274 | 0.77 | LMNA (0.49) | LMNACYP2C19MAOAMAOBBCHE | |
| SCHEMBL567024 | 0.76 | ALDH1A1 (0.43) | LMNACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199794-A1 | Monomers and Polymers with Pendant Aspirin and Compositions and Methods Thereof | UNIVERSITY OF MASSACHUSETTS | 2024-06-20 | — | — | US | disclosed |
| WO-2022221026-A1 | MONOMERS AND POLYMERS WITH PENDANT ASPIRIN, AND COMPOSITIONS AND METHODS THEREOF | UNIVERSITY OF MASSACHUSETTS (US) | 2022-10-20 | — | — | WO | disclosed |
| US-20120035341-A1 | PROCEDE DE POLYMERISATION PAR VOIE CATALYTIQUE DE 1,4-DIOXANES-2,5-DIONES ET LES POLYMERES CORRESPONDANTS | MINASOLVE (FR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010123349-A1 | SYSTEM FOR CONTROLLED DRUG DELIVERY COMPRISING BIODEGRADABLE POLYMER MICROPARTICLES | UNIVERSITEIT UTRECHT HOLDING B.V. (NL) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010100390-A1 | CATALYTIC POLYMERIZATION METHOD FOR 1,4-DIOXANE-2,5-DIONES, AND CORRESPONDING POLYMERS | MINASOLVE (FR) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199794-A1 | Monomers and Polymers with Pendant Aspirin and Compositions and Methods Thereof | PTGIS, PTGS1, PTGIR | LMNA 3482/4885AKT1 2976/4885TAAR1 2084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.