Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159573 | 0.86 | KIF11 (0.46) | MAPK1MAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL9316251 | 0.86 | TSHR (0.35) | KMT2AALDH1A1HDAC1ESR1ESR2 | |
| SCHEMBL2121344 | 0.79 | MAPK1 (0.44) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL6225960 | 0.78 | MAPK1 (0.48) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL6209830 | 0.75 | KMT2A (0.50) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL10483069 | 0.75 | KCNN4 (0.46) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL3847927 | 0.75 | KIF11 (0.41) | MAPTHDAC8 | |
| SCHEMBL18396557 | 0.75 | RAB9A (0.41) | MAPK1MAPTKMT2AALDH1A1HDAC3 | |
| SCHEMBL15259639 | 0.75 | TSHR (0.46) | MAPK1MAPTKMT2ACYP2C19HIF1A | |
| SCHEMBL11331205 | 0.75 | MAPK1 (0.41) | MAPK1MAPTKMT2ACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010679-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-01-11 | — | — | US | claimed |
| WO-2022107049-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-05-27 | — | — | WO | claimed |
| EP-3714893-A1 | CHEMICAL CROSSLINKERS | Amicus Therapeutics, Inc. (US) | 2020-09-30 | — | — | EP | claimed |
| EP-2976092-B1 | CHEMICAL CROSSLINKERS | AMICUS THERAPEUTICS INC (US) | 2020-04-22 | — | — | EP | claimed |
| US-20180185503-A1 | CHEMICAL CROSSLINKERS | AMICUS THERAPEUTICS, INC. (US) | 2018-07-05 | — | — | US | claimed |
| WO-2017013593-A1 | ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS | LUPIN LIMITED (IN) | 2017-01-26 | — | — | WO | claimed |
| US-20160129126-A1 | CHEMICAL CROSSLINKERS | AMICUS THERAPEUTICS, INC. (US) | 2016-05-12 | — | — | US | claimed |
| EP-2976092-A2 | CHEMICAL CROSSLINKERS | Amicus Therapeutics, Inc. (US) | 2016-01-27 | — | — | EP | claimed |
| WO-2014143734-A2 | CHEMICAL CROSSLINKERS | AMICUS THERAPEUTICS, INC. (US) | 2014-09-18 | — | — | WO | claimed |
| WO-2014143701-A1 | CHEMICAL CROSSLINKERS | AMICUS THERAPEUTICS, INC. (US) | 2014-09-18 | — | — | WO | claimed |
| WO-2007006534-A2 | PIPERIDINE DERIVATIVES USEFUL IN THE DIAGNOSTIC AND THERAPEUTIC TREATMENT OF DISEASES DEPENDING ON RENIN ACTIVITY | NOVARTIS AG (CH) | 2007-01-18 | — | — | WO | claimed |
| EP-1362029-B1 | HYDROXY-PEROXYESTER PREPARATION METHOD | ARKEMA (FR) | 2005-09-14 | — | — | EP | claimed |
| US-6887877-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-05-03 | — | — | US | claimed |
| US-6875740-B1 | Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-05 | — | — | US | claimed |
| US-20040176632-A1 | Catalytic polymerization of vinyl chloride with bases with peroxy compounds | ATOFINA (FR) | 2004-09-09 | — | — | US | claimed |
| US-20030229053-A1 | Compounds and methods for the treatment or prevention of flavivirus infections | SHIRE BIOCHEM INC. (CA) | 2003-12-11 | — | — | US | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010679-A1 | ANTINOCICEPTIVE COMPOUNDS AND USES THEREOF | OPRL1, OPRK1, OPRD1 | MAPK1 3216/4885MAPT 1174/4885KMT2A 2212/4885 |
| US-20030229053-A1 | Compounds and methods for the treatment or prevention of flavivirus infections | HAVCR2, ZC3HAV1, MAVS | MAPK1 636/4885MAPT 1891/4885KMT2A 3263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.