Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249588 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BALOX15CES2 | |
| SCHEMBL31588806 | 0.83 | KDM4E (0.44) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL5034762 | 0.79 | KDM4E (0.42) | MTNR1AMTNR1BNPC1RAB9AKMT2A | |
| SCHEMBL6139382 | 0.79 | STING1 (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL8170739 | 0.79 | ALDH1A1 (0.45) | MTNR1AMTNR1BNPC1RAB9AKMT2A | |
| SCHEMBL5723078 | 0.77 | PDE4A (0.49) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7171635 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL11842947 | 0.76 | CNR2 (0.47) | MTNR1AMTNR1BALOX15NPC1RAB9A | |
| SCHEMBL28382464 | 0.76 | ALOX15 (0.50) | MTNR1AMTNR1BALOX15CES2 | |
| SCHEMBL1398744 | 0.76 | NPC1 (0.48) | NPC1RAB9AKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148240-B2 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI-AVENTIS (FR) | 2006-12-12 | — | — | US | disclosed |
| US-6949583-B2 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same | SANOFI-SYNTHELABO (FR) | 2005-09-27 | — | — | US | disclosed |
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI (FR) | 2004-01-15 | — | — | US | disclosed |
| US-20030225100-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same | SANOFI (FR) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT1 | MTNR1A 3074/4885MTNR1B 2847/4885ALOX15 135/4885 |
| US-20030225100-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method of preparing same and compositions containing same | NR2C2, NR4A2, NR5A2 | MTNR1A 65/4885MTNR1B 87/4885ALOX15 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.