Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PYGL | P06737 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675986 | 0.83 | HDAC2 (0.47) | HDAC2NPC1RXFP1RAB9AKDM4E | |
| SCHEMBL5896865 | 0.82 | LEF1 (0.54) | HDAC2NPC1RXFP1RAB9AKDM4E | |
| SCHEMBL19453004 | 0.81 | ALDH1A1 (0.52) | HDAC2NPC1RXFP1RAB9AKDM4E | |
| SCHEMBL5897014 | 0.79 | TP53 (0.48) | HDAC2NPC1RXFP1RAB9AKDM4E | |
| SCHEMBL5676237 | 0.79 | TP53 (0.52) | NPC1RXFP1RAB9AKDM4EPYGL | |
| SCHEMBL5897662 | 0.78 | NHERF1 (0.56) | NPC1RXFP1RAB9AKDM4EPYGL | |
| SCHEMBL6617197 | 0.78 | LEF1 (0.58) | NPC1RXFP1RAB9AKDM4EPYGL | |
| SCHEMBL1415238 | 0.77 | KDM4E (0.61) | HDAC2NPC1RAB9AKDM4EPYGL | |
| SCHEMBL5897347 | 0.76 | ITGB3 (0.54) | HDAC2NHERF1ITGB3ITGA2BHRAS | |
| SCHEMBL5889839 | 0.75 | HDAC2 (0.56) | HDAC2NPC1RXFP1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556035-A4 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECH INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1556035-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026264-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |