Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087408 | 0.85 | LEF1 (0.59) | LEF1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5896864 | 0.85 | LEF1 (0.51) | LEF1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5897606 | 0.84 | LEF1 (0.50) | LEF1HDAC2KDM4ENPC1RAB9A | |
| SCHEMBL5677239 | 0.84 | ALOX15 (0.49) | HDAC2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5896829 | 0.82 | LEF1 (0.47) | LEF1HDAC2KDM4ENPC1RAB9A | |
| SCHEMBL5676002 | 0.82 | HDAC2 (0.47) | HDAC2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5675986 | 0.82 | HDAC2 (0.47) | HDAC2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL20287496 | 0.80 | HDAC1 (0.57) | HDAC2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL19453004 | 0.80 | ALDH1A1 (0.52) | HDAC2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL5896935 | 0.79 | LEF1 (0.58) | LEF1KDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | LEF1 1977/4885HDAC2 750/4885KDM4E 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.