Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904354 | 0.89 | NFE2L2 (0.39) | SLC40A1SLC22A12NFE2L2KMT2AMEN1 | |
| SCHEMBL294598 | 0.82 | GAA (0.46) | HTR6SLC22A12KMT2AMEN1GAA | |
| SCHEMBL5713263 | 0.75 | COMT (0.38) | NFE2L2KMT2AMEN1RAB9AGAA | |
| SCHEMBL7760171 | 0.71 | GAA (0.34) | KMT2AMEN1GAA | |
| SCHEMBL4930571 | 0.71 | HTR6 (0.53) | HTR6KMT2AGAA | |
| SCHEMBL3136914 | 0.66 | MYC (0.41) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL9360088 | 0.65 | HSD11B1 (0.54) | HTR6KMT2AMEN1GAACA2 | |
| SCHEMBL8178997 | 0.65 | HSD11B1 (0.32) | GAA | |
| SCHEMBL28212024 | 0.65 | KMT2A (0.58) | HTR6KMT2AMEN1RAB9AMET | |
| SCHEMBL29874131 | 0.64 | MEN1 (0.60) | HTR6SLC22A12KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631456-A2 | 1-4-DIHYDROPYRIDINE-CONTAINING IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PRODUCTION OF IMAGEABLE ELEMENTS | Kodak Polychrome Graphics GmbH (DE) | 2006-03-08 | — | — | EP | disclosed |
| WO-2005001571-A2 | 1-4-DIHYDROPYRIDINE-CONTAINING IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PRODUCTION OF IMAGEABLE ELEMENTS | KODAK POLYCHROME GRAPHICS GMBH (DE) | 2005-01-06 | — | — | WO | disclosed |