Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | FABP6 | P51161 | 2/20 | 0.50 |
| ▸ | TYMS | P04818 | 3/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679441 | 0.85 | MASP2 (0.47) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| SCHEMBL1887281 | 0.84 | PLAU (0.61) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| SCHEMBL31651401 | 0.84 | PLAU (0.61) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| SCHEMBL5679180 | 0.81 | TAAR1 (0.50) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| SCHEMBL1170649 | 0.79 | KDM4E (0.52) | ALDH1A1ALPLALPIALPGKDM4E | |
| SCHEMBL29449363 | 0.79 | MEN1 (0.57) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| SCHEMBL118057 | 0.79 | MEN1 (0.57) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| SCHEMBL26075185 | 0.79 | FABP6 (0.59) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| SCHEMBL11363764 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MASP2MEN1NUDT1KMT2A | |
| Hydrochloric Acid SCHEMBL6621838 | 0.78 | MEN1 (0.55) | ALDH1A1MASP2MEN1NUDT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | claimed |
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-05-30 | — | — | US | claimed |
| CN-122079899-A | Application of pharmaceutical composition in preparation of medicines for preventing or treating diseases related to Sirttail 7 protein | — | 2026-05-26 | — | — | CN | disclosed |
| US-20260125348-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4710922-A2 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | Oregon State University (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4003337-B1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | UNIV OREGON STATE (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12473262-B2 | Aryl hydrocarbon receptor activators | OREGON STATE UNIVERSITY (US) | 2025-11-18 | — | — | US | disclosed |
| US-20240116897-A1 | BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2024-04-11 | — | — | US | disclosed |
| EP-4269394-A1 | BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2023-11-01 | — | — | EP | disclosed |
| CN-114989096-B | Thioazole compound and preparation method and application thereof | 赣南师范大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116829542-A | Benzothiazole and benzimidazole derivatives, pharmaceutically acceptable salts, preparation method thereof and pharmaceutical composition containing same as active ingredient | 韩国化学研究院 | 2023-09-29 | — | — | CN | disclosed |
| US-20100136136-A1 | JAK-2 Modulators and Methods of Use | EXELIXIS, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100136136-A1 | JAK-2 Modulators and Methods of Use | EXELIXIS, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| EP-2061768-A2 | IMIDAZOLE-4,5-DICARBOXAMIDE DERIVATIVES AS JAK-2 MODULATORS | Exelixis, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20090076063-A1 | Carboxamide compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | US | disclosed |
| WO-2008042282-A2 | IMIDAZOLE-4, 5-DICARBOXAMIDE DERIVATIVES AS JAK-2 MODULATORS | EXELIXIS, INC. (US) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008042282-A2 | IMIDAZOLE-4, 5-DICARBOXAMIDE DERIVATIVES AS JAK-2 MODULATORS | EXELIXIS, INC. (US) | 2008-04-10 | — | — | WO | disclosed |
| EP-1887002-A1 | CARBOXAMIDE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-20060089316-A1 | Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof | BROWN TRUMAN R | 2006-04-27 | — | — | US | disclosed |
| US-5326779-A | Method of inhibiting the advanced glycosylation of proteins using 1,2-disubstituted-benzimidazoles | THE ROCKEFELLER UNIVERSITY (US) | 1994-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136136-A1 | JAK-2 Modulators and Methods of Use | JAK2, JAK1, JAK3 | ALDH1A1 4295/4885MASP2 1959/4885MEN1 3504/4885 |
| US-20060089316-A1 | Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof | ALDOA, FBP1, GYS2 | ALDH1A1 450/4885MASP2 99/4885MEN1 1158/4885 |
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | FLNB, BRI3BP, CCNI | ALDH1A1 1841/4885MASP2 698/4885MEN1 3710/4885 |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | FLNB, BRI3BP, CCNI | ALDH1A1 1841/4885MASP2 698/4885MEN1 3710/4885 |
| US-20090076063-A1 | Carboxamide compound and use of the same | CBR3, SIRT2, SIRT1 | ALDH1A1 3016/4885MASP2 4005/4885MEN1 700/4885 |
| US-20260125348-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | AHR, ARNT, NR1H2 | ALDH1A1 2105/4885MASP2 3021/4885MEN1 4553/4885 |
| US-20240116897-A1 | BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | SIRT7, SIRT1, BRD7 | ALDH1A1 776/4885MASP2 4053/4885MEN1 2217/4885 |
| US-12473262-B2 | Aryl hydrocarbon receptor activators | AHR, ARNT, NR0B1 | ALDH1A1 787/4885MASP2 2416/4885MEN1 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.