Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795332 | 0.72 | ADRA1A (0.44) | ADRA1ASIGMAR1CYP11B2IDO1PDPK1 | |
| SCHEMBL1504258 | 0.72 | ADRA1A (0.41) | ADRA1ASIGMAR1CYP11B2IDO1PDPK1 | |
| SCHEMBL29187306 | 0.70 | ADRA1A (0.45) | ADRA1ASIGMAR1CYP11B2IDO1PDPK1 | |
| SCHEMBL6285498 | 0.69 | CASP3 (0.41) | SLC18A3 | |
| SCHEMBL29390302 | 0.69 | SIGMAR1 (0.62) | ADRA1ASIGMAR1CYP11B2KDM1AMAOA | |
| SCHEMBL503849 | 0.69 | SIGMAR1 (0.62) | ADRA1ASIGMAR1CYP11B2KDM1AMAOA | |
| SCHEMBL4278950 | 0.69 | ADRA1A (0.51) | ADRA1ASIGMAR1CYP11B2IDO1PDPK1 | |
| SCHEMBL30788464 | 0.68 | ADRA1A (0.43) | ADRA1ASIGMAR1CYP11B2IDO1PDPK1 | |
| SCHEMBL30606845 | 0.68 | SIGMAR1 (0.60) | ADRA1ASIGMAR1CYP11B2KDM1AMAOA | |
| Ammonia Solution, Strong SCHEMBL8210515 | 0.68 | SIGMAR1 (0.60) | ADRA1ASIGMAR1CYP11B2KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622966-A1 | POLYMER NETWORKS | The University of Reading (GB) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004094504-A1 | POLYMER NETWORKS | THE UNIVERSITY OF READING (GB) | 2004-11-04 | — | — | WO | disclosed |