Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | EEF2K | O00418 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685248 | 0.80 | EEF2K (0.50) | CNR2GAAEEF2KCES2CES1 | |
| SCHEMBL6261167 | 0.76 | CNR2 (0.43) | CNR2GAAEEF2KHIF1ACES2 | |
| SCHEMBL362441 | 0.76 | LMNA (0.62) | ATMSLC6A3HPGDLMNAPOLB | |
| SCHEMBL13234917 | 0.73 | ATM (0.51) | ATMGAASLC6A3MEN1KMT2A | |
| SCHEMBL11097152 | 0.71 | ATM (0.57) | ATMSLC6A3MEN1KMT2AHPGD | |
| SCHEMBL6443530 | 0.71 | EEF2K (0.50) | CNR2GAAEEF2KHIF1ACES2 | |
| SCHEMBL9538880 | 0.71 | ATM (0.81) | ATMSLC6A3KDM4ELMNAPOLB | |
| SCHEMBL25118925 | 0.70 | GAA (0.46) | CNR2GAAHIF1ACES2CES1 | |
| SCHEMBL5684903 | 0.70 | ATM (0.51) | CNR2ATMSLC6A3CES2CES1 | |
| SCHEMBL2049574 | 0.69 | HPGD (0.59) | ATMSLC6A3HPGDLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640359-A2 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 2006-03-29 | — | — | EP | claimed |