SCHEMBL5685184

SCHEMBL5685184

C[Si](C)(C)C1(Cc2ccccc2)CCCCO1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
OPRL1 P41146 3/20 0.34
OPRM1 P35372 2/20 0.34
OPRK1 P41145 1/20 0.34
GAA P10253 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27532470 0.85 OPRM1 (0.37) MAOAMAOBOPRL1OPRM1OPRK1
Ammonia Solution, Strong SCHEMBL4767628 0.74 MAOA (0.42) MAOAMAOBOPRL1OPRM1OPRK1
SCHEMBL14778149 0.73 MAOA (0.41) MAOAMAOBOPRL1OPRM1OPRK1
SCHEMBL60702 0.72 MAOA (0.41) MAOAMAOBOPRL1OPRM1OPRK1
SCHEMBL14778815 0.72 MAOA (0.43) MAOAMAOBMEN1KMT2AL3MBTL1
SCHEMBL5486438 0.72 MAOA (0.38) MAOAMAOBOPRL1OPRM1OPRK1
SCHEMBL9694869 0.72 MAOA (0.38) MAOAMAOBOPRL1OPRM1OPRK1
SCHEMBL28450686 0.72 SIGMAR1 (0.38) MEN1KMT2A
SCHEMBL27668036 0.71 MAOA (0.40) MAOAMAOBOPRL1OPRM1OPRK1
Methane SCHEMBL14661843 0.71 MAOA (0.37) MAOAMAOBOPRL1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0960655-B1 Method for grinding silicon metalloid DOW CORNING (US) 2006-03-15 EP disclosed
EP-0960655-A2 Method for grinding silicon metalloid DOW CORNING CORPORATION (US) 1999-12-01 EP disclosed