Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612247 | 1.00 | TSHR (0.46) | TSHRMAPK1DAOALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL17559541 | 0.98 | TSHR (0.45) | TSHRMAPK1DAOALDH1A1KDM4E | |
| Acetic Acid SCHEMBL28177239 | 0.87 | ALDH1A1 (0.47) | TSHRMAPK1DAOALDH1A1KDM4E | |
| SCHEMBL27976418 | 0.85 | TSHR (0.36) | TSHRMAPK1DAOALDH1A1KDM4E | |
| SCHEMBL20594952 | 0.84 | KDM4E (0.38) | TSHRMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL20554634 | 0.82 | TLR8 (0.40) | TSHRMAPK1DAOALDH1A1SMN1; SMN2 | |
| Propionic Acid SCHEMBL28311891 | 0.82 | AGBL2 (0.45) | DAOALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL24534066 | 0.82 | KDM4E (0.36) | TSHRMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL16895182 | 0.82 | KDM4E (0.36) | TSHRMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL3749196 | 0.82 | CYP11B1 (0.43) | DAOALDH1A1KIF11CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066257-A2 | HETEROCYLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | Sugen, Inc. (US) | 2001-01-10 | — | — | EP | claimed |
| WO-1999048868-A9 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN INC (US) | 2000-04-20 | — | — | WO | claimed |
| WO-1999048868-A2 | HETEROCYCLIC CLASSES OF COMPOUNDS FOR THE MODULATING TYROSINE PROTEIN KINASE | SUGEN, INC. (US) | 1999-09-30 | — | — | WO | claimed |
| US-4762928-A | PESTICIDES, MEDICINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-08-09 | — | — | US | claimed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | claimed |
| US-12617801-B2 | Tetrahydrothieno pyridine derivatives as DDRS inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-05-05 | — | — | US | disclosed |
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| EP-4713323-A1 | 3-CARBONYL IMIDAZO[1,5-A]PYRIDINE DERIVATIVES FOR USE AS CD38 INHIBITORS FOR THE TREATMENT OF CNS DISORDERS | Cerevance, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-20260069571-A1 | DDR1 AND DDR2 INHIBITORS FOR THE TREATEMENT OF CANCER AND FIBROTIC DISEASES | REDX PHARMA PLC (GB) | 2026-03-12 | — | — | US | disclosed |
| US-20260028328-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-01-29 | — | — | US | disclosed |
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INST NAT SANTE RECH MED (FR) | 2025-12-18 | — | — | US | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
| US-4762928-A | PESTICIDES, MEDICINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| US-4762928-A | PESTICIDES, MEDICINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-08-09 | — | — | US | disclosed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
| EP-0228846-A1 | Amino-trifluoromethylpyridine compound and process for preparing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617801-B2 | Tetrahydrothieno pyridine derivatives as DDRS inhibitors | DDR1, DDR2, DDRGK1 | TSHR 163/4885MAPK1 458/4885DAO 2241/4885 |
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | BBOX1, NDUFB6, NDUFB5 | TSHR 2969/4885MAPK1 774/4885DAO 923/4885 |
| US-20260069571-A1 | DDR1 AND DDR2 INHIBITORS FOR THE TREATEMENT OF CANCER AND FIBROTIC DISEASES | DDR1, DDR2, TGFBR2 | TSHR 302/4885MAPK1 657/4885DAO 2569/4885 |
| US-20260028328-A1 | HETEROARYL DERIVATIVES AS DDRs INHIBITORS | DDR1, DDR2, DDRGK1 | TSHR 118/4885MAPK1 1764/4885DAO 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.