Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.76 |
| ▸ | CHEK2 | O96017 | 12/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | MMP9 | P14780 | 1/20 | 0.66 |
| ▸ | MMP8 | P22894 | 1/20 | 0.66 |
| ▸ | MMP13 | P45452 | 1/20 | 0.66 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SCD | O00767 | 2/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.56 |
| ▸ | MPL | P40238 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490323 | 0.90 | HDAC6 (0.86) | HDAC6CHEK2SCDNPBWR1 | |
| SCHEMBL30884657 | 0.86 | HDAC6 (0.94) | HDAC6CHEK2SCDNPBWR1 | |
| Ensulizole SCHEMBL38724 | 0.86 | HDAC6 (1.00) | HDAC6CHEK2KDM4EALDH1A1HPGD | |
| Ensulizole SCHEMBL7751558 | 0.86 | HDAC6 (1.00) | HDAC6CHEK2KDM4EALDH1A1HPGD | |
| Ensulizole SCHEMBL1276071 | 0.85 | HDAC6 (0.97) | HDAC6CHEK2KDM4EALDH1A1HPGD | |
| Ensulizole SCHEMBL17351654 | 0.85 | HDAC6 (0.97) | HDAC6CHEK2KDM4EALDH1A1HPGD | |
| Ensulizole SCHEMBL28708898 | 0.85 | HDAC6 (0.97) | HDAC6CHEK2KDM4EALDH1A1HPGD | |
| SCHEMBL5219768 | 0.84 | NR4A2 (0.83) | HDAC6CHEK2MMP2MMP9MMP8 | |
| SCHEMBL20982511 | 0.84 | MMP2 (0.78) | HDAC6CHEK2MMP2MMP9MMP8 | |
| SCHEMBL5178280 | 0.84 | HDAC6 (0.84) | HDAC6CHEK2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1690855-B1 | Composition comprising phenylene-bis-benzimidazol-tetrasulfonic acid disodium salt | SYMRISE AG (DE) | 2014-01-22 | — | — | EP | claimed |
| EP-1690855-B1 | Composition comprising phenylene-bis-benzimidazol-tetrasulfonic acid disodium salt | SYMRISE AG (DE) | 2014-01-22 | — | — | EP | disclosed |
| EP-1690855-A1 | Process for the preparation of phenylene-bis-benzimidazol-tetrasulfonic acid disodium salt | Symrise GmbH & Co. KG (DE) | 2006-08-16 | — | — | EP | disclosed |
| EP-1339697-B1 | METHOD FOR PRODUCING A PHENYLENE-BIS-BENZIMIDAZOLE-TETRASULFONIC ACID DISODIUM SALT | SYMRISE GMBH & CO KG (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-6730795-B2 | REACTING O-PHENYLENE-DIAMINE WITH TEREPHTHALIC ACID AND CHLOROSULFONIC ACID IN THE PRESENCE OF STRONG ACIDS TO PRODUCE PHENYLENE-BIS-BENZIMIDAZOLE- TETRASULFONIC ACID DI-SODIUM SALT | SYMRISE GMBH & CO. KG (DE) | 2004-05-04 | — | — | US | disclosed |
| EP-1339697-A1 | METHOD FOR PRODUCING A PHENYLENE-BIS-BENZIMIDAZOLE-TETRASULFONIC ACID DISODIUM SALT | HAARMANN & REIMER GMBH (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-20020082429-A1 | Process for the preparation of phenylene-bis-benzimidazole-tetrasulfonic acid disodium salt | SYMRISE AG (DE) | 2002-06-27 | — | — | US | disclosed |
| WO-2002044155-A1 | METHOD FOR PRODUCING A PHENYLENE-BIS-BENZIMIDAZOLE-TETRASULFONIC ACID DISODIUM SALT | HAARMANN & REIMER GMBH (DE) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082429-A1 | Process for the preparation of phenylene-bis-benzimidazole-tetrasulfonic acid disodium salt | TST, FHIT, NISCH | HDAC6 605/4885CHEK2 1620/4885MMP2 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.