Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 16/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23004926 | 0.85 | ACHE (0.68) | ACHEDRD2DRD3HTR1AHTR2A | |
| SCHEMBL2793079 | 0.85 | DRD2 (0.50) | ACHEDRD2 | |
| Hydrochloric Acid SCHEMBL1625872 | 0.84 | DRD2 (0.49) | ACHEDRD2 | |
| Hydrochloric Acid SCHEMBL10415650 | 0.84 | DRD2 (0.49) | ACHEDRD2 | |
| SCHEMBL1581878 | 0.78 | ACHE (0.67) | ACHEDRD2DRD3HTR1AHTR2A | |
| SCHEMBL8169616 | 0.77 | ACHE (0.52) | ACHEDRD2DRD3HTR1AHTR2A | |
| SCHEMBL3739379 | 0.77 | GBA1 (0.42) | ACHEDRD2DRD3SLC6A4 | |
| SCHEMBL5646802 | 0.76 | GBA1 (0.47) | HTR2ASLC6A4HTR2C | |
| Hydrochloric Acid SCHEMBL9633666 | 0.74 | GBA1 (0.46) | SLC6A4 | |
| SCHEMBL8470807 | 0.74 | DRD2 (1.00) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160851-A1 | Substituted piperidine carbamates | NOVO NORDISK A/S (DK) | 2006-07-20 | — | — | US | disclosed |
| EP-1636207-A1 | SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004111032-A1 | SUBSTITUTED PIPERIDINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | disclosed |
| US-4885302-A | 2-((4-Piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapy | SYNTHELABO, 58, RUE DE LA GLACIERE - 75013 PARIS | 1989-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160851-A1 | Substituted piperidine carbamates | LIPE, PNLIP, LIPC | ACHE 73/4885DRD2 2554/4885DRD3 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.