Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5689641 | 0.90 | BRD4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29612297 | 0.88 | TOP1 (0.32) | KDRTOP1 | |
| Hydrochloric Acid SCHEMBL5689832 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4475556 | 0.85 | TOP1 (0.32) | TOP1 | |
| Hydrochloric Acid SCHEMBL5689877 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL4471078 | 0.82 | DRD2 (0.34) | TOP1 | |
| Hydrochloric Acid SCHEMBL6889704 | 0.78 | DRD2 (0.32) | KDR | |
| Hydrochloric Acid SCHEMBL2522711 | 0.77 | BRD4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6889965 | 0.76 | DRD2 (0.31) | — | |
| SCHEMBL5836727 | 0.76 | JAK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511755-B1 | TRANSITION METAL COMPOUNDS THEIR PREPARATION AND THEIR USE IN CATALYST SYSTEMS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2006-03-08 | — | — | EP | disclosed |
| US-20050182266-A1 | Transition metal componds their preparation and their use in catalyst systems for the polymerization and copolymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182266-A1 | Transition metal componds their preparation and their use in catalyst systems for the polymerization and copolymerization of olefins | YAP1, COX14, CYCS | KDR 2739/4885TOP1 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.