Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPY2R | P49146 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5687800 | 0.89 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL5688070 | 0.86 | KMT2A (0.41) | ALDH1A1NPY2RKMT2ANPC1LMNA | |
| SCHEMBL5687627 | 0.81 | NPC1 (0.51) | SMN1; SMN2ALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL5687639 | 0.81 | CXCR1 (0.49) | SMN1; SMN2ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL5687502 | 0.81 | CXCR1 (0.46) | SMN1; SMN2ALDH1A1KMT2ANPC1LMNA | |
| SCHEMBL5687145 | 0.78 | PKM (0.49) | SMN1; SMN2ALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL5646367 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL5689973 | 0.76 | MCHR1 (0.45) | SMN1; SMN2ALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL5687198 | 0.76 | NPC1 (0.45) | SMN1; SMN2ALDH1A1KMT2AKDM4ENPC1 | |
| SCHEMBL5647960 | 0.76 | CXCR1 (0.56) | SMN1; SMN2GAAKMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160865-A1 | Pyridinyl carbamates | NOVO NORDISK A/S (DK) | 2006-07-20 | — | — | US | claimed |
| EP-1636205-A1 | PYRIDINYL CARBAMATES AS HORMONE-SENSITIVE LIPASE INHIBITORS | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | claimed |
| WO-2004111031-A1 | PYRIDINYL CARBAMATES AS HORMONE-SENSITIVE LIPASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | claimed |
| US-20060160865-A1 | Pyridinyl carbamates | NOVO NORDISK A/S (DK) | 2006-07-20 | — | — | US | disclosed |
| EP-1636205-A1 | PYRIDINYL CARBAMATES AS HORMONE-SENSITIVE LIPASE INHIBITORS | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004111031-A1 | PYRIDINYL CARBAMATES AS HORMONE-SENSITIVE LIPASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160865-A1 | Pyridinyl carbamates | LIPE, PNLIP, LPL | SMN1; SMN2 2486/4885ALDH1A1 2231/4885NPY2R 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.