Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5690604 | 0.95 | ENPP2 (0.48) | ENPP2ALDH1A1P2RX7GAAHTT | |
| SCHEMBL5691183 | 0.81 | ITGB1 (0.60) | ENPP2ALDH1A1KMT2AITGB1ITGA4 | |
| SCHEMBL5690873 | 0.81 | ITGB1 (0.60) | ENPP2ALDH1A1KMT2AITGB1ITGA4 | |
| SCHEMBL6308859 | 0.81 | ALDH1A1 (0.52) | ENPP2ALDH1A1FOLH1KMT2AITGB1 | |
| SCHEMBL5690382 | 0.75 | ITGB1 (0.53) | ENPP2ALDH1A1KMT2AITGB1ITGA4 | |
| SCHEMBL5690403 | 0.74 | ENPP2 (0.47) | ENPP2ALDH1A1GAAHTTNPC1 | |
| SCHEMBL5852341 | 0.73 | PTPN2 (0.48) | ALDH1A1P2RX7GAAKMT2ANPC1 | |
| SCHEMBL5690885 | 0.72 | ITGB1 (0.58) | ALDH1A1ITGB1ITGA4MAPK1L3MBTL1 | |
| SCHEMBL5690356 | 0.72 | ENPP2 (0.48) | ENPP2ALDH1A1GAAHTTNPC1 | |
| SCHEMBL12771582 | 0.72 | ENPP2 (0.65) | ENPP2ALDH1A1KMT2AHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001974-B1 | 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2006-05-24 | — | — | EP | claimed |