Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.49 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297633 | 0.90 | PTGDR2 (0.63) | PTGER1PTGDR2SMN1; SMN2USP28USP25 | |
| SCHEMBL17049367 | 0.85 | CCR5 (0.56) | PTGER1PTGDR2SMN1; SMN2USP28USP25 | |
| SCHEMBL6760570 | 0.81 | CYP4F2 (0.51) | PTGER1KMT2A | |
| SCHEMBL8613905 | 0.79 | ERN1 (0.47) | PTGER1USP28USP25MAOBLRRK2 | |
| SCHEMBL8616112 | 0.79 | USP28 (0.45) | PTGER1SMN1; SMN2USP28USP25MAOB | |
| SCHEMBL224277 | 0.79 | KDM1A (0.55) | PTGER1SMN1; SMN2USP28USP25MAOB | |
| SCHEMBL30739242 | 0.79 | KDM1A (0.55) | PTGER1SMN1; SMN2USP28USP25MAOB | |
| SCHEMBL8613429 | 0.78 | USP28 (0.44) | PTGER1USP28USP25LRRK2HTT | |
| SCHEMBL8616532 | 0.78 | KDM1A (0.46) | PTGER1SMN1; SMN2USP28USP25MAOB | |
| SCHEMBL8617807 | 0.78 | KDM1A (0.46) | PTGER1SMN1; SMN2USP28USP25MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227086-B1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-6518257-B1 | 1-substituted phenyl-1-(1h-imidazol-4-yl) alcohols, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227086-A1 | 1-SUBSTITUTED PHENYL-1-(1H-IMIDAZOL-4-YL) ALCOHOLS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |