Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 1.00 |
| ▸ | CA12 | O43570 | 9/20 | 1.00 |
| ▸ | CA1 | P00915 | 9/20 | 1.00 |
| ▸ | CA2 | P00918 | 9/20 | 1.00 |
| ▸ | CA9 | Q16790 | 9/20 | 1.00 |
| ▸ | MMP8 | P22894 | 8/20 | 1.00 |
| ▸ | MMP1 | P03956 | 6/20 | 1.00 |
| ▸ | MMP9 | P14780 | 4/20 | 1.00 |
| ▸ | MMP3 | P08254 | 3/20 | 1.00 |
| ▸ | MMP13 | P45452 | 1/20 | 1.00 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854279 | 1.00 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL4861903 | 1.00 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL4855712 | 1.00 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL569074 | 1.00 | MMP2 (1.00) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL530223 | 0.75 | MMP2 (0.60) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL4285508 | 0.75 | MMP2 (0.60) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL2940123 | 0.75 | MMP2 (0.60) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL14534604 | 0.75 | MMP2 (0.60) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL1987041 | 0.75 | MMP2 (0.60) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL2938943 | 0.75 | MMP2 (0.60) | MMP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345033-B2 | Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2008-03-18 | — | — | US | claimed |
| US-20060111328-A1 | Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-05-25 | — | — | US | claimed |
| EP-1611143-A2 | NEW CARBAMOYL-AND THIOCARBAMOYL-PHOSPHONATES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-01-04 | — | — | EP | claimed |
| WO-2004089962-A2 | NEW CARBAMOYL-AND THIOCARBAMOYL-PHOSPHONATES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-10-21 | — | — | WO | claimed |
| US-20250090586-A1 | METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF | ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) | 2025-03-20 | — | — | US | disclosed |
| US-12076347-B2 | Methods for production of platelets from pluripotent stem cells and compositions thereof | ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) | 2024-09-03 | — | — | US | disclosed |
| US-11971402-B2 | Methods and reagents for determination and treatment of organotropic metastasis | CORNELL UNIVERSITY (US) | 2024-04-30 | — | — | US | disclosed |
| US-20230067928-A1 | METHODS FOR PROGNOSING AND PREVENTING METASTATIC LIVER DISEASE | UNIV CORNELL (US) | 2023-03-02 | — | — | US | disclosed |
| US-20230028239-A1 | METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF | ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) | 2023-01-26 | — | — | US | disclosed |
| US-11400118-B2 | Methods for production of platelets from pluripotent stem cells and compositions thereof | ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) | 2022-08-02 | — | — | US | disclosed |
| US-11397182-B2 | Methods for prognosing and preventing metastatic liver disease | CORNELL UNIVERSITY (US) | 2022-07-26 | — | — | US | disclosed |
| CN-114558032-A | Method for preparing platelets from pluripotent stem cells and composition thereof | 安斯泰来再生医药协会 | 2022-05-31 | — | — | CN | disclosed |
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-02-09 | — | — | US | disclosed |
| EP-2393495-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089752-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-08-12 | — | — | WO | disclosed |
| US-7345033-B2 | Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2008-03-18 | — | — | US | disclosed |
| US-7345033-B2 | Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2008-03-18 | — | — | US | disclosed |
| US-20060111328-A1 | Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-05-25 | — | — | US | disclosed |
| EP-1611143-A2 | NEW CARBAMOYL-AND THIOCARBAMOYL-PHOSPHONATES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089962-A2 | NEW CARBAMOYL-AND THIOCARBAMOYL-PHOSPHONATES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | MMP9, MMP26, MMP25 | MMP2 10/4885CA12 307/4885CA1 247/4885 |
| US-20060111328-A1 | Carbamoyl-and thiocarbamoyl-phosphonates and pharmaceutical compositions comprising them | P2RY1, PLCB1, PLCB3 | MMP2 4697/4885CA12 1139/4885CA1 841/4885 |
| US-20230028239-A1 | METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF | THPO, PDGFRA, PDGFRB | MMP2 3559/4885CA12 3978/4885CA1 4210/4885 |
| US-11400118-B2 | Methods for production of platelets from pluripotent stem cells and compositions thereof | THPO, PDGFRA, PDGFRB | MMP2 3559/4885CA12 3978/4885CA1 4210/4885 |
| US-20250090586-A1 | METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF | THPO, PDGFRA, PDGFRB | MMP2 3559/4885CA12 3978/4885CA1 4210/4885 |
| US-12076347-B2 | Methods for production of platelets from pluripotent stem cells and compositions thereof | THPO, PDGFRA, PDGFRB | MMP2 3559/4885CA12 3978/4885CA1 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.