Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523209 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2CA2TRPA1ATM | |
| SCHEMBL8390355 | 0.77 | GABRA1 (0.42) | GABRA1GABRB2CA2TRPA1ATM | |
| SCHEMBL7520240 | 0.76 | GABRA1 (0.38) | GABRA1GABRB2CA2 | |
| SCHEMBL7525374 | 0.74 | ALDH1A1 (0.36) | GABRA1GABRB2TRPA1ATM | |
| SCHEMBL8441767 | 0.73 | TRPA1 (0.43) | TRPA1ATM | |
| SCHEMBL7526769 | 0.71 | TRPA1 (0.37) | TRPA1ATM | |
| SCHEMBL7514801 | 0.71 | ALDH1A1 (0.38) | GABRA1GABRB2CA2 | |
| SCHEMBL8379346 | 0.70 | TRPA1 (0.33) | TRPA1ATM | |
| SCHEMBL8439852 | 0.69 | ALDH1A1 (0.41) | GABRA1GABRB2CA2 | |
| SCHEMBL27535171 | 0.69 | ESR1 (0.39) | CA2TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468692-B1 | Use of 2,6-di-alkyl-4-silyl-phenols for treating xanthoma | MERRELL PHARMA INC (US) | 2006-04-26 | — | — | EP | claimed |