Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520207 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL7520590 | 0.80 | GABRA1 (0.30) | CA2GABRA1GABRB2 | |
| SCHEMBL7520240 | 0.80 | GABRA1 (0.38) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL7526427 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1CA2GABRA1 | |
| SCHEMBL8389494 | 0.78 | CA2 (0.42) | ALDH1A1TSHRCA2GABRA1GABRB2 | |
| SCHEMBL8441767 | 0.74 | TRPA1 (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8442028 | 0.71 | GABRA1 (0.36) | TSHRGABRA1GABRB2 | |
| SCHEMBL8440795 | 0.70 | GABRA1 (0.41) | TSHRCA2GABRA1GABRB2 | |
| SCHEMBL8441588 | 0.69 | P4HB (0.34) | — | |
| SCHEMBL5692154 | 0.69 | GABRA1 (0.41) | CA2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962435-A | ANTICHOLESTEROL AGENT | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| US-5677291-A | Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols | HOECHST MARION ROUSSEL, INC. (US) | 1997-10-14 | — | — | US | disclosed |