Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298696 | 0.83 | NPC1 (0.38) | BACE1MEN1KMT2AALDH1A1GFER | |
| SCHEMBL5693368 | 0.82 | RAPGEF4 (0.43) | BACE1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL5692977 | 0.77 | MEN1 (0.47) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL1417373 | 0.76 | L3MBTL1 (0.54) | MEN1KMT2AALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL456056 | 0.75 | KDM4E (0.55) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL5692943 | 0.73 | CD38 (0.42) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL5693381 | 0.71 | PRMT6 (0.47) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL11248387 | 0.70 | MAOA (0.48) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL5692951 | 0.69 | NPC1 (0.51) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL11480561 | 0.69 | POLB (0.45) | ALDH1A1TDP1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280791-B1 | N-HETEROARYLMETHYL-M-PHENYLENEDIAMINE DERIVATIVE-CONTAINING DYES FOR KERATIN FIBERS AND NOVEL N-HETEROARYLMETHYL-M-PHENYLENEDIAMINE DERIVATIVES | WELLA AG (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-6997961-B2 | N-heteroarylmethyl-m-phenylenediamine derivatives-containing dyes for keratin fibers and novel n-heteroarylmethyl-m-phenylenediamine derivatives | WELLA AG (DE) | 2006-02-14 | — | — | US | disclosed |
| US-20050081310-A1 | N-heteroarylmethyl-m-phenylenediamine derivatives-containing dyes for keratin fibers and novel n-heteroarylmethyl-m-phenylenediamine derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2005-04-21 | — | — | US | disclosed |
| EP-1280791-A1 | N-HETEROARYLMETHYL-M-PHENYLENEDIAMINE DERIVATIVE-CONTAINING DYES FOR KERATIN FIBERS AND NOVEL N-HETEROARYLMETHYL-M-PHENYLENEDIAMINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2003-02-05 | — | — | EP | disclosed |
| WO-2002072568-A1 | N-HETEROARYLMETHYL-M-PHENYLENEDIAMINE DERIVATIVE-CONTAINING DYES FOR KERATIN FIBERS AND NOVEL N-HETEROARYLMETHYL-M-PHENYLENEDIAMINE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050081310-A1 | N-heteroarylmethyl-m-phenylenediamine derivatives-containing dyes for keratin fibers and novel n-heteroarylmethyl-m-phenylenediamine derivatives | KRT18, VIM, KPNB1 | BACE1 4344/4885MEN1 3323/4885KMT2A 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.