Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalazine SCHEMBL2692127 | 0.93 | ALDH1A1 (0.65) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL27818244 | 0.91 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL1270969 | 0.88 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL29349552 | 0.88 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL32661377 | 0.88 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL2774 | 0.88 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL29822171 | 0.88 | ALDH1A1 (1.00) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Phthalazine SCHEMBL1924788 | 0.86 | ALDH1A1 (0.54) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL23202414 | 0.85 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 | |
| Quinoline SCHEMBL5714730 | 0.85 | ALDH1A1 (0.94) | ALDH1A1NPC1POLBRAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109072019-A | Peeling layer comprising at least one fluorosilicone compound | 美国陶氏有机硅公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109072039-A | Adhesive delamination layer comprising at least one of silsesquioxane polymer and silane for display substrate processing | 美国陶氏有机硅公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107207500-A | Dicyclic compound and combinations thereof and medical usage | 阿迪维纳斯治疗有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-107074860-A | Methods for preparing TOLL-like receptor modulators | 吉利德科学公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-102256068-B | Solid state image pickup device and imaging device | FUJI FILM CORP. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-102256068-A | Solid-state imaging device and imaging apparatus | FUJIFILM CORP | 2011-11-23 | — | — | CN | disclosed |
| EP-1646718-A2 | METHODS FOR THE STEREOSELECTIVE SYNTHESIS AND ENANTIOMERIC ENRICHMENT OF B-AMINO ACIDS | Pharmacia Corporation (US) | 2006-04-19 | — | — | EP | disclosed |
| US-20050159401-A1 | Texaphyrin coordination compounds and uses thereof | PHARMACYCLICS, INC. | 2005-07-21 | — | — | US | disclosed |
| WO-2005005633-A2 | METHODS FOR THE STEREOSELECTIVE SYNTHESIS AND ENANTIOMERIC ENRICHMENT OF B-AMINO ACIDS | PHARMACIA CORPORATION (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159401-A1 | Texaphyrin coordination compounds and uses thereof | GPX4, TEX13A, TXN2 | ALDH1A1 4247/4885NPC1 2968/4885POLB 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.