Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28812905 | 0.85 | IGF1R (0.45) | IGF1RALOX15CNR1CNR2PPARA | |
| SCHEMBL4509532 | 0.84 | TRPA1 (0.48) | ALDH1A1KDM4EGAAMAPTTDP1 | |
| SCHEMBL31528718 | 0.82 | KAT8 (0.52) | ALDH1A1KDM4EESR1CYP3A4IGF1R | |
| SCHEMBL5319451 | 0.82 | KAT8 (0.52) | ALDH1A1KDM4EESR1CYP3A4IGF1R | |
| SCHEMBL3828797 | 0.80 | ALDH1A1 (0.59) | ALDH1A1BACE1KDM4EALOX5GAA | |
| SCHEMBL26382894 | 0.79 | APP (0.46) | ALDH1A1ALOX5GAA | |
| SCHEMBL123763 | 0.76 | ESR1 (0.59) | ALDH1A1ALOX5GAATDP1ESR1 | |
| SCHEMBL745012 | 0.76 | ESR1 (0.59) | ALDH1A1TDP1ESR1ESR2CYP3A4 | |
| SCHEMBL9278716 | 0.76 | ESR2 (0.48) | ALDH1A1KDM4EALOX5GAAMAPT | |
| SCHEMBL29547368 | 0.76 | ESR1 (0.59) | ALDH1A1TDP1ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305320-B1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SC HOLDING AG (CH) | 2006-05-31 | — | — | EP | disclosed |
| CN-1170824-C | Benzotriazole UV absorbent | �������⻯ѧƷ�ع�����˾ | 2004-10-13 | — | — | CN | disclosed |
| US-6677392-B2 | USED TO STABILIE NATURAL, SEMI-SYNTHETIC OR SYNTHETIC POLYMER. | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-01-13 | — | — | US | disclosed |
| EP-1305320-A1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-6515051-B2 | Stability and durability and a low loss rate when incorporated into automotive coatings; soluble in a variety of substrates including thermoplastic polymers and often are colorless | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-6458872-B1 | FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-10-01 | — | — | US | disclosed |
| US-20020115753-A1 | Photostable, silylated benzotriazole UV absorbers and compositions stabilized therewith | RAVICHANDRAN RAMANATHAN (US) | 2002-08-22 | — | — | US | disclosed |
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-07-25 | — | — | US | disclosed |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-05-30 | — | — | US | disclosed |
| WO-2002012252-A1 | PHOTOSTABLE, SILYLATED BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |
| US-6262151-B1 | FOR AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-6166218-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| CN-1265395-A | Benzotriazole UV absorbent | CIBA SC HOLDING AG (CH) | 2000-09-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | ALDH1A1 970/4885BACE1 1917/4885KDM4E 174/4885 |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | ALDH1A1 970/4885BACE1 1917/4885KDM4E 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.