Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 4/20 | 0.55 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 3/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790474 | 0.88 | NT5E (0.57) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL517711 | 0.85 | CASP6 (0.54) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL6018444 | 0.84 | CASP6 (0.43) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL5028738 | 0.83 | CASP6 (0.54) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL5694580 | 0.83 | CTRB1 (0.48) | CASP6CYP1A2ALDH1A1TDP1MAPT | |
| SCHEMBL22919235 | 0.81 | NSD2 (0.42) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL4078302 | 0.80 | CASP6 (0.49) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL27514313 | 0.80 | ENPP2 (0.46) | PHLPP2ENPP2CYP1A2ALDH1A1TDP1 | |
| SCHEMBL14339180 | 0.79 | ALDH1A1 (0.38) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL29215781 | 0.79 | CASP6 (0.57) | CASP6NSD2DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8175860-B2 | Method of inhibiting the growth of Helicobacter pylori | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-08 | — | — | US | disclosed |