Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569538 | 0.76 | KDM4E (0.38) | PTPN1GAA | |
| Acetic Acid SCHEMBL3446495 | 0.76 | MEN1 (0.45) | PSEN1PTPN1 | |
| SCHEMBL11611168 | 0.72 | LMNA (0.42) | PSEN1 | |
| SCHEMBL9332096 | 0.66 | PSEN1 (0.43) | PSEN1 | |
| SCHEMBL10615005 | 0.65 | PSEN1 (0.38) | PSEN1 | |
| SCHEMBL660156 | 0.61 | ALOX5 (0.31) | — | |
| SCHEMBL6976213 | 0.61 | ALOX5 (0.31) | — | |
| SCHEMBL10445564 | 0.61 | — | — | |
| SCHEMBL7799058 | 0.60 | ALOX5 (0.45) | — | |
| SCHEMBL16282031 | 0.60 | ALOX5 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664264-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | SANDERS BOB G (US) | 2012-10-04 | — | — | US | disclosed |
| US-8148424-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-20100303899-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2010-12-02 | — | — | US | disclosed |
| US-7718814-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-7608638-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-20080161349-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080119514-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2008-05-22 | — | — | US | disclosed |
| US-7312232-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-6645998-B2 | Treatment of a cell proliferative disease | RESEARCH DEVELOPMENT FOUNDATION | 2003-11-11 | — | — | US | disclosed |
| US-20020156024-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION | 2002-10-24 | — | — | US | disclosed |
| US-6417223-B1 | ANTIPROLIFERATION AGENTS OR APOTOPSIS | RESEARCH DEVELOPMENT FOUNDATION | 2002-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303899-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TST, TXNRD3, TXNRD1 | PSEN1 3935/4885CNR1 699/4885CNR2 790/4885 |
| US-20020156024-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | HCCS, TTPA, TST | PSEN1 4461/4885CNR1 641/4885CNR2 536/4885 |
| US-20080161349-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TST, TXNRD3, TXNRD1 | PSEN1 3869/4885CNR1 634/4885CNR2 795/4885 |
| US-20080119514-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TXN, TXN2, TTPA | PSEN1 2772/4885CNR1 2460/4885CNR2 2762/4885 |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | TST, TXNRD3, TXNRD1 | PSEN1 3935/4885CNR1 699/4885CNR2 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.