SCHEMBL5695818

SCHEMBL5695818

FC(F)(F)c1ccc(-c2ccccc2I)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.56
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
BACE1 P56817 2/20 0.43
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAOB P27338 1/20 0.41
CHUK O15111 1/20 0.41
TXNRD1 Q16881 1/20 0.41
NOX4 Q9NPH5 1/20 0.41
JAK2 O60674 1/20 0.41
GPR3 P46089 1/20 0.39
TOP1 P11387 1/20 0.39
NTRK1 P04629 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17840160 0.84 KIF11 (0.68) KIF11ALDH1A1TSHRBACE1KDM4E
SCHEMBL8025255 0.82 KIF11 (0.65) KIF11ALDH1A1TSHRBACE1KDM4E
SCHEMBL11310344 0.80 KIF11 (0.77) KIF11ALDH1A1TSHRBACE1KDM4E
SCHEMBL1109665 0.79 S1PR1 (0.42) KIF11ALDH1A1TSHRMEN1KMT2A
SCHEMBL29511323 0.79 KIF11 (0.45) KIF11BACE1GPR3TOP1
SCHEMBL31096463 0.79 S1PR1 (0.42) KIF11ALDH1A1TSHRMEN1KMT2A
SCHEMBL21620303 0.79 MAOB (0.50) ALDH1A1TSHRKDM4EMAOB
SCHEMBL10304733 0.77 KIF11 (0.40) KIF11BACE1MAOBJAK2
SCHEMBL16844169 0.77 KIF11 (0.58) KIF11ALDH1A1TSHRBACE1KDM4E
SCHEMBL30394422 0.77 KIF11 (0.58) KIF11ALDH1A1TSHRBACE1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174392-B1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-03-18 EP disclosed
EP-3174392-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO Dow AgroSciences LLC (US) 2017-06-07 EP disclosed
US-9550739-B2 Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto DOW AGROSCIENCES LLC (US) 2017-01-24 US disclosed
WO-2016018872-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-02-04 WO disclosed
US-20160024026-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-01-28 US disclosed
EP-1651360-A1 METAL CONTAINERS HAVING AN EASILY OPENABLE END AND METHOD OF MANUFACTURING THE SAME Valspar Sourcing, Inc. (US) 2006-05-03 EP disclosed
WO-2005011880-A1 METAL CONTAINERS HAVING AN EASILY OPENABLE END AND METHOD OF MANUFACTURING THE SAME VALSPAR SOURCING, INC. (US) 2005-02-10 WO disclosed
EP-0985165-A1 IONIC HALOMETHYL-1,3,5-TRIAZINE PHOTOINITIATORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-03-15 EP disclosed
US-5939237-A OVERCOATINGS FOR PHOTOSENSITIVE ARTICLES AND IMAGES IMATION CORP. (US) 1999-08-17 US disclosed
US-5847133-A Ionic halomethyl-1,3,5-triazine photoinitiators MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-08 US disclosed
EP-0585164-A1 Use of alkali soluble photopolymer in color proofing constructions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-03-02 EP disclosed
US-5235015-A HIGH SPEED AQUEOUS SOLVENT DEVELOPABLE PHOTOPOLYMER COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-10 US disclosed
EP-0538997-A1 Aminoketone sensitizers for aqueous soluble photopolymer compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-04-28 EP disclosed
US-5153104-A Negative-acting photothermographic imaging systems comprising also a nitrate, an initiator, a leuco dye and a binder; colorfastness; clean background MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-06 US disclosed
EP-0500321-A1 High speed aqueous solvent developable photopolymer compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-26 EP disclosed
EP-0462763-A1 Thermally developable light-sensitive layers containing photobleachable sensitizers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-27 EP disclosed
EP-0061898-B1 VISIBLE LIGHT SENSITIVE, THERMALLY DEVELOPABLE IMAGING SYSTEMS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-19 EP disclosed
US-4460677-A Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-17 US disclosed
US-4386154-A ACYLATED LEUCO DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-05-31 US disclosed
EP-0061898-A1 Visible light sensitive, thermally developable imaging systems MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024026-A1 MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO ACHE, DDT, MLYCD KIF11 2397/4885ALDH1A1 238/4885TSHR 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.