Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695960 | 0.79 | DRD1 (0.42) | PTGS2DRD1HPGDKDM4EALDH1A1 | |
| SCHEMBL5695950 | 0.73 | DRD1 (0.38) | PTGS2DRD1HPGDKDM4EALDH1A1 | |
| SCHEMBL5695952 | 0.73 | DRD1 (0.40) | PTGS2DRD1HPGDKDM4EALDH1A1 | |
| SCHEMBL5695964 | 0.71 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL742011 | 0.69 | PKM (0.46) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11152641 | 0.67 | HPGD (0.47) | HPGDKDM4EALDH1A1LMNARECQL | |
| SCHEMBL28764074 | 0.65 | HPGD (0.41) | HPGDKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10589802 | 0.64 | POLB (0.36) | PTGS2HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL12220338 | 0.64 | TDP1 (0.53) | HPGDKDM4EALDH1A1LMNARECQL | |
| SCHEMBL11879645 | 0.64 | TSHR (0.47) | ALDH1A1LMNAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138108-B2 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | L'OREAL (FR) | 2006-11-21 | — | — | US | claimed |
| EP-1371654-B1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | OREAL (FR) | 2006-06-14 | — | — | EP | claimed |
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | SOCIETE L'OREAL S.A. (FR) | 2004-02-26 | — | — | US | claimed |
| EP-1371654-A1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | L'OREAL (FR) | 2003-12-17 | — | — | EP | claimed |
| US-7138108-B2 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | L'OREAL (FR) | 2006-11-21 | — | — | US | disclosed |
| EP-1371654-B1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | OREAL (FR) | 2006-06-14 | — | — | EP | disclosed |
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | SOCIETE L'OREAL S.A. (FR) | 2004-02-26 | — | — | US | disclosed |
| EP-1371654-A1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | L'OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | ARSA, CUTA, AHR | PTGS2 3111/4885DRD1 3980/4885HPGD 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.