Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696006 | 0.87 | HTT (0.36) | HTTLIG1USP2GAAKMT2A | |
| SCHEMBL5695950 | 0.81 | DRD1 (0.38) | DRD1HTTKMT2AHPGDMAPK1 | |
| SCHEMBL5696010 | 0.79 | PTGS2 (0.38) | DRD1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL5695952 | 0.77 | DRD1 (0.40) | DRD1HTTUSP2HPGDMAPK1 | |
| SCHEMBL9469860 | 0.75 | SQOR (0.44) | DRD1HTTLIG1GAAKMT2A | |
| SCHEMBL6111939 | 0.73 | GAA (0.50) | DRD1HTTLIG1USP2GAA | |
| SCHEMBL515196 | 0.73 | ADRB2 (0.59) | HTTLIG1USP2GAAKMT2A | |
| SCHEMBL19921086 | 0.72 | ADRB2 (0.48) | DRD1HTTLIG1GAAKMT2A | |
| SCHEMBL9431758 | 0.71 | RXRA (0.61) | HTTLIG1USP2GAAKMT2A | |
| SCHEMBL29107282 | 0.70 | SYK (0.54) | DRD1HTTLIG1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138108-B2 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | L'OREAL (FR) | 2006-11-21 | — | — | US | claimed |
| EP-1371654-B1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | OREAL (FR) | 2006-06-14 | — | — | EP | claimed |
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | SOCIETE L'OREAL S.A. (FR) | 2004-02-26 | — | — | US | claimed |
| EP-1371654-A1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | L'OREAL (FR) | 2003-12-17 | — | — | EP | claimed |
| US-7138108-B2 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | L'OREAL (FR) | 2006-11-21 | — | — | US | disclosed |
| EP-1371654-B1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | OREAL (FR) | 2006-06-14 | — | — | EP | disclosed |
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | SOCIETE L'OREAL S.A. (FR) | 2004-02-26 | — | — | US | disclosed |
| EP-1371654-A1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | L'OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | ARSA, CUTA, AHR | DRD1 3980/4885HTT 501/4885LIG1 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.