SCHEMBL5696246

SCHEMBL5696246

COc1ccc(S(=O)(=O)n2cc(C(=O)O)cc2-c2cc(OC)c(OC)c(OC)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
TUBB4A P04350 5/20 0.44
TUBB P07437 5/20 0.44
TUBA3C P0DPH7 5/20 0.44
TUBA1B P68363 5/20 0.44
TUBA4A P68366 5/20 0.44
TUBB4B P68371 5/20 0.44
TUBB3 Q13509 5/20 0.44
TUBB2A Q13885 5/20 0.44
TUBB8 Q3ZCM7 5/20 0.44
TUBA3E Q6PEY2 5/20 0.44
TUBA1A Q71U36 5/20 0.44
TUBA1C Q9BQE3 5/20 0.44
TUBB6 Q9BUF5 5/20 0.44
TUBB2B Q9BVA1 5/20 0.44
TUBB1 Q9H4B7 5/20 0.44
TAS2R14 Q9NYV8 4/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3371555 0.82 CA12 (0.43) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL3369368 0.81 TUBB1 (0.44) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1378956 0.78 CYP11B1 (0.47) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5696178 0.77 RAPGEF4 (0.53) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5696184 0.77 KMT2A (0.52) L3MBTL1ALDH1A1PKMKMT2A
SCHEMBL1375760 0.75 CYP11B2 (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL1375792 0.75 FYN (0.46) CA12CA1CA2CA9KMT2A
SCHEMBL1155963 0.73 TP53 (0.48) L3MBTL1PPARGALDH1A1CA9KMT2A
SCHEMBL1379606 0.73 MAP3K11 (0.48) L3MBTL1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL3368168 0.73 L3MBTL1 (0.38) L3MBTL1ALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1655284-A1 2-Phenylsulfopyrroles Aponetics AG (CH) 2006-05-10 EP disclosed