Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369368 | 0.81 | TUBB1 (0.44) | RAPGEF4CA12CA1CA2CA9 | |
| SCHEMBL28456535 | 0.80 | RAPGEF4 (0.57) | RAPGEF4HTR6HTR1ADRD2HTR2A | |
| SCHEMBL3371555 | 0.80 | CA12 (0.43) | RAPGEF4HTR6CA12CA1CA2 | |
| SCHEMBL5696246 | 0.77 | L3MBTL1 (0.47) | CA12CA1CA2CA9TUBB4A | |
| SCHEMBL1375760 | 0.76 | CYP11B2 (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11932215 | 0.73 | RAPGEF4 (0.66) | RAPGEF4HTR6CA1CA2L3MBTL1 | |
| SCHEMBL1375792 | 0.72 | FYN (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL18040304 | 0.72 | MAPT (0.54) | HTR6TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3368168 | 0.71 | L3MBTL1 (0.38) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL3368043 | 0.71 | TUBB4A (0.44) | CA12CA1CA2CA9TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655284-A1 | 2-Phenylsulfopyrroles | Aponetics AG (CH) | 2006-05-10 | — | — | EP | disclosed |