Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CD69 | Q07108 | 4/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28378641 | 0.90 | KMT2A (0.55) | KMT2ACD69PTGDR2SMN1; SMN2ELANE | |
| SCHEMBL830740 | 0.84 | KMT2A (0.60) | ALDH1A1KMT2ACD69SMN1; SMN2KDM4E | |
| SCHEMBL321504 | 0.78 | L3MBTL1 (0.56) | ALDH1A1KMT2ACD69PTGDR2SMN1; SMN2 | |
| SCHEMBL28044483 | 0.78 | KMT2A (0.53) | ALDH1A1KMT2ACD69PTGDR2SMN1; SMN2 | |
| SCHEMBL11333666 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAANLRP3SMN1; SMN2KDM4E | |
| SCHEMBL20509554 | 0.77 | ALDH1A1 (0.60) | ALDH1A1KMT2ACD69PTGDR2SMN1; SMN2 | |
| SCHEMBL1887188 | 0.77 | KMT2A (0.77) | GAAKMT2ACD69PTGDR2KDM4E | |
| SCHEMBL27090170 | 0.77 | NAMPT (0.71) | ALDH1A1KMT2ASMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL6743332 | 0.75 | POLB (0.62) | ALDH1A1KMT2ACD69PTGDR2SMN1; SMN2 | |
| SCHEMBL16479215 | 0.75 | ALDH1A1 (0.61) | ALDH1A1GAANLRP3SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054052-B1 | Stabilized hydrotreated and hydrodewaxed lubricant compositions | CIBA SC HOLDING AG (CH) | 2006-06-28 | — | — | EP | claimed |
| US-6410490-B1 | OIL ADDITIVE MIXTURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-25 | — | — | US | claimed |
| EP-1054052-A2 | Stabilized hydrotreated and hydrodewaxed lubricant compositions | Ciba SC Holding AG (CH) | 2000-11-22 | — | — | EP | claimed |
| EP-1054052-B1 | Stabilized hydrotreated and hydrodewaxed lubricant compositions | CIBA SC HOLDING AG (CH) | 2006-06-28 | — | — | EP | disclosed |
| US-6410490-B1 | OIL ADDITIVE MIXTURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-25 | — | — | US | disclosed |
| EP-1054052-A2 | Stabilized hydrotreated and hydrodewaxed lubricant compositions | Ciba SC Holding AG (CH) | 2000-11-22 | — | — | EP | disclosed |