SCHEMBL5696296

SCHEMBL5696296

COC(=O)c1cc(Cl)ccc1OC(=O)Oc1ccc(Cl)cc1C(=O)OC

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.56
KMT2A Q03164 4/20 0.50
MEN1 O00255 2/20 0.50
NR4A2 P43354 2/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49
MAPT P10636 2/20 0.47
KCNMA1 Q12791 2/20 0.46
GAA P10253 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7414042 0.88 ABL1 (0.54) ABL1KMT2AMEN1NR4A2ALDH1A1
SCHEMBL29812845 0.86 MEN1 (0.64) ABL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL1095516 0.86 MEN1 (0.64) ABL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL10890222 0.84 LMNA (0.51) ABL1KMT2AMEN1NR4A2ALDH1A1
SCHEMBL2946505 0.83 SLC6A3 (0.68) ABL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL7397469 0.82 ABL1 (0.55) ABL1KMT2AMEN1NR4A2ALDH1A1
SCHEMBL30801345 0.82 ABL1 (0.55) ABL1KMT2AMEN1NR4A2ALDH1A1
SCHEMBL13159046 0.82 KMT2A (0.48) ABL1KMT2AMEN1NR4A2ALDH1A1
SCHEMBL17133624 0.81 ABL1 (0.54) ABL1KMT2AMEN1NR4A2ALDH1A1
SCHEMBL17040919 0.80 SMN1; SMN2 (0.58) ABL1KMT2AMEN1NR4A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1444288-B1 METHOD OF MAKING BLOCK COPOLYMERS BY SOLID STATE POLYMERIZATION GEN ELECTRIC (US) 2006-06-07 EP disclosed
US-6960641-B2 Method of making block copolymers by solid state polymerization GENERAL ELECTRIC COMPANY (US) 2005-11-01 US disclosed
EP-1444288-A1 METHOD OF MAKING BLOCK COPOLYMERS BY SOLID STATE POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 2004-08-11 EP disclosed
US-20040138383-A1 Method of making block copolymers by solid state polymerization SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2004-07-15 US disclosed
US-20030139529-A1 Method of making block copolymers by solid state polymerization GENERAL ELECTRIC COMPANY 2003-07-24 US disclosed
WO-2003040208-A1 METHOD OF MAKING BLOCK COPOLYMERS BY SOLID STATE POLYMERIZATION GENERAL ELECTRIC COMPANY (US) 2003-05-15 WO disclosed