Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570366 | 0.75 | KMT2A (0.49) | HCAR2DAO | |
| SCHEMBL2198685 | 0.72 | IKBKB (0.43) | HCAR2 | |
| SCHEMBL569780 | 0.69 | BRD4 (0.48) | HCAR2GPR35DAODYRK1B | |
| SCHEMBL569702 | 0.69 | PLA2G10 (0.47) | HCAR2DAO | |
| SCHEMBL570062 | 0.68 | PIN1 (0.47) | HCAR2 | |
| SCHEMBL17065994 | 0.68 | HCAR2 (0.55) | HCAR2DAO | |
| SCHEMBL570152 | 0.66 | HCAR2 (0.45) | HCAR2DAO | |
| SCHEMBL27658275 | 0.66 | HAO2 (0.54) | HCAR2 | |
| SCHEMBL4964605 | 0.65 | HAO2 (0.53) | HCAR2 | |
| SCHEMBL16197762 | 0.65 | ALPL (0.46) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |