Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570062 | 0.79 | PIN1 (0.47) | HCAR2KDM4E | |
| SCHEMBL4964605 | 0.75 | HAO2 (0.53) | HCAR2 | |
| SCHEMBL16197762 | 0.75 | ALPL (0.46) | HCAR2KDM4EIKBKB | |
| SCHEMBL570366 | 0.73 | KMT2A (0.49) | HCAR2KDM4EDAOKDR | |
| SCHEMBL27658275 | 0.73 | HAO2 (0.54) | HCAR2KDM4E | |
| SCHEMBL16883789 | 0.72 | ALK (0.48) | GPR35HCAR2KDM4EIKBKB | |
| SCHEMBL2198685 | 0.71 | IKBKB (0.43) | HCAR2KDM4EIKBKB | |
| SCHEMBL569461 | 0.71 | PIN1 (0.56) | HCAR2 | |
| SCHEMBL570152 | 0.70 | HCAR2 (0.45) | HCAR2DAOKIT | |
| SCHEMBL569692 | 0.69 | HCAR2 (0.41) | GPR35HCAR2DYRK1BDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |