Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697016 | 0.78 | KDM4E (0.52) | KDM4EMEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL15963172 | 0.76 | LTA4H (0.53) | LTA4HMAPTLMNAPKMCXCR4 | |
| SCHEMBL14025005 | 0.76 | LMNA (0.59) | LTA4HLMNAPKMCXCR4KDM4E | |
| SCHEMBL2904306 | 0.74 | SIGMAR1 (0.62) | LTA4HLMNAPKMPOLBGAA | |
| SCHEMBL6659263 | 0.73 | GAA (0.32) | LMNAKDM4EGAAMEN1KMT2A | |
| SCHEMBL14287705 | 0.70 | HRH3 (0.67) | CHRM2HRH3ALDH1A1 | |
| SCHEMBL14107874 | 0.69 | CRBN (0.40) | LTA4HMAPTLMNAPKMNPSR1 | |
| SCHEMBL14287706 | 0.67 | HRH3 (0.76) | HRH3 | |
| SCHEMBL17468364 | 0.66 | CXCR4 (0.55) | LMNACXCR4POLBKDM4EGAA | |
| SCHEMBL20478197 | 0.66 | NQO1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325939-B1 | Process for preparing co-gels having polyazacycloalkane moieties and their use | AIR LIQUIDE (FR) | 2006-06-14 | — | — | EP | claimed |
| EP-1325939-A2 | Process for preparing co-gels having polyazacycloalkane moieties and their use | L'Air Liquide S. A. à Directoire et Conseil de Surveillance pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) | 2003-07-09 | — | — | EP | claimed |
| EP-1051422-B1 | SILICA GEL INCORPORATING POLYAZACYCLOALKANE STRUCTURAL UNITS | AIR LIQUIDE (FR) | 2003-07-02 | — | — | EP | claimed |
| US-6524372-B1 | Separation and purification of gases; 1,4,8,11-Tetrakis(3-(triethoxysilyl)propyl)-1,4,8,11 -tetraazacyclotetradecane | L′Air Liquide, Societe Anonyme a Directoire et Conseil de Surveillance pour l′Etude et l′Exploitation des Procedes Georges Claude (FR) | 2003-02-25 | — | — | US | claimed |
| EP-1325939-B1 | Process for preparing co-gels having polyazacycloalkane moieties and their use | AIR LIQUIDE (FR) | 2006-06-14 | — | — | EP | disclosed |
| EP-1325939-A2 | Process for preparing co-gels having polyazacycloalkane moieties and their use | L'Air Liquide S. A. à Directoire et Conseil de Surveillance pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) | 2003-07-09 | — | — | EP | disclosed |
| EP-1051422-B1 | SILICA GEL INCORPORATING POLYAZACYCLOALKANE STRUCTURAL UNITS | AIR LIQUIDE (FR) | 2003-07-02 | — | — | EP | disclosed |
| US-6524372-B1 | Separation and purification of gases; 1,4,8,11-Tetrakis(3-(triethoxysilyl)propyl)-1,4,8,11 -tetraazacyclotetradecane | L′Air Liquide, Societe Anonyme a Directoire et Conseil de Surveillance pour l′Etude et l′Exploitation des Procedes Georges Claude (FR) | 2003-02-25 | — | — | US | disclosed |