SCHEMBL5698133

SCHEMBL5698133

N=C1C=CC2=C(C1)Sc1cc(N)ccc1N2

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ APAF1 O14727 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12812969 0.83 CA9 (0.33) NOX1KDM4EMEN1APAF1GAA
SCHEMBL8982039 0.80 MAPT (0.36) NOX1MAPT
Hydrochloric Acid SCHEMBL1813065 0.80 KDM4E (0.31) NOX1KDM4EMEN1APAF1GAA
Hydrochloric Acid SCHEMBL1756449 0.79 MAPT (0.35) NOX1MAPT
Hydrochloric Acid SCHEMBL1814021 0.79 KDM4E (0.33) NOX1KDM4EMEN1APAF1GAA
SCHEMBL11287177 0.77 KDM4E (0.31) NOX1KDM4EMEN1APAF1GAA
SCHEMBL29625245 0.70 SNCA (0.50) NOX1KDM4EMEN1APAF1GAA
SCHEMBL64975 0.70 SNCA (0.50) NOX1KDM4EMEN1APAF1GAA
SCHEMBL29600380 0.70 SNCA (0.50) NOX1KDM4EMEN1APAF1GAA
Hydrochloric Acid SCHEMBL31175976 0.69 SNCA (0.48) NOX1KDM4EMEN1APAF1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017032699-A1 METHOD FOR PRODUCING LOW-BOILING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2017-03-02 — — WO disclosed
US-20060287548-A1 Radical interceptors as stabilizers of polymerizable compounds BASF AKTIENGESELLSCHAFT (DE) 2006-12-21 — — US disclosed
WO-2006122923-A1 AROMATIC HETEROCYCLES AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-11-23 — — WO disclosed
EP-1670877-A1 RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-21 — — EP disclosed
EP-1565728-A1 METHOD FOR DETERMINING THE QUANTITY OF POLYMER SEPARATED FROM (METH)ACRYLIC ACID AND/OR (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2005-08-24 — — EP disclosed
WO-2005030907-A1 RADICAL INTERCEPTORS AS STABILIZERS OF POLYMERIZABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2005-04-07 — — WO disclosed
EP-1518916-A1 Scavenger of free radicals as stabilizers of polymerisable compounds BASF AKTIENGESELLSCHAFT (DE) 2005-03-30 — — EP disclosed
WO-2004104050-A1 METHOD FOR THE PRODUCTION, TREATMENT AND FURTHER PROCESSING OF POLYMERISABLE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2004-12-02 — — WO disclosed
WO-2004038391-A1 METHOD FOR DETERMINING THE QUANTITY OF POLYMER SEPARATED FROM (METH)ACRYLIC ACID AND/OR (METH)ACRYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2004-05-06 — — WO disclosed
US-20040082737-A1 Determination of the amount of polymer deposited from (meth) acrylic acid and/or (meth) acrylic esters BASF AKTIENGESELLSCHAFT (DE) 2004-04-29 — — US disclosed
EP-0159513-A1 Enzymatic inorganic phosphate assay Miles Italiana SpA (IT) 1985-10-30 — — EP disclosed
US-4338180-A SURFACE-CHALCOGENATED MOLYBENUM OR TUNGSTEN; SOLAR CELLS KURARAY CO., LTD. (JP) 1982-07-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287548-A1 Radical interceptors as stabilizers of polymerizable compounds TTPA, AADAT, TSPO NOX1 1537/4885KDM4E 4307/4885MEN1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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