Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982039 | 0.99 | MAPT (0.36) | MAPTNOX1 | |
| SCHEMBL3112042 | 0.83 | MAPT (0.36) | MAPTNOX1 | |
| Hydrochloric Acid SCHEMBL1813062 | 0.82 | MAPT (0.35) | MAPTNOX1 | |
| SCHEMBL11286802 | 0.82 | MAPT (0.35) | MAPTNOX1 | |
| SCHEMBL17363623 | 0.81 | MAPT (0.34) | MAPT | |
| Hydrochloric Acid SCHEMBL4227553 | 0.80 | MAPT (0.34) | MAPT | |
| SCHEMBL6470714 | 0.79 | LRRK2 (0.36) | MAPT | |
| SCHEMBL5698133 | 0.79 | NOX1 (0.33) | MAPTNOX1 | |
| Hydrochloric Acid SCHEMBL8441856 | 0.75 | MAPT (0.39) | MAPT | |
| Hydromethylthionine SCHEMBL31159644 | 0.74 | SNCA (0.48) | MAPTNOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9121776-B2 | Welding arc apparel with UV or thermochromic activated images | LINCOLN GLOBAL, INC. (US) | 2015-09-01 | — | — | US | disclosed |
| WO-2014053907-A2 | WELDING ARC APPAREL WITH UV OR THERMOCHROMIC ACTIVATED IMAGES | LINCOLN GLOBAL, INC. (US) | 2014-04-10 | — | — | WO | disclosed |
| WO-2014020386-A1 | WELDING ACCESSORY WITH UV OR THERMOCHROMIC ACTIVATED IMAGES; SYSTEM FORAND METHOD OF DETECTING A THRESHOLD TEMPERATURE OF THERMAL RADIATION EXPOSURE DURING WELDING OPERATIONS | LINCOLN GLOBAL, INC. (US) | 2014-02-06 | — | — | WO | disclosed |
| US-20130026150-A1 | WELDING ARC APPAREL WITH UV OR THEMOCHROMIC ACTIVATED IMAGES | LINCOLN GLOBAL, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-8284385-B2 | Welding arc apparel with UV activated images | LINCOLN GLOBAL, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| EP-2498945-A2 | WELDING ARC APPAREL WITH UV ACTIVATED IMAGES AND METHOD FOR DETECTING UV RADIATION | Lincoln Global, Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| US-20110116076-A1 | WELDING ARC APPAREL WITH UV ACTIVATED IMAGES | LINCOLN GLOBAL, INC. (US) | 2011-05-19 | — | — | US | disclosed |
| WO-2011058431-A2 | WELDING ARC APPAREL WITH UV ACTIVATED IMAGES AND METHOD FOR DETECTING UV RADIATION | LINCOLN GLOBAL, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| US-20090169745-A1 | Nanoparticle based inks and methods of making the same | KIMBERLY-CLARK WORLDWIDE, INC. | 2009-07-02 | — | — | US | disclosed |
| US-20080166262-A1 | Medical packaging substrate with security feature | NEENAH, INC. FORMERLY KNOWN AS NEENAH PAPER, INC. | 2008-07-10 | — | — | US | disclosed |
| EP-0799246-A1 | IMPROVED MUTABLE COMPOSITION | Kimberly-Clark Worldwide, Inc. (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5645964-A | STABILIZERS | KIMBERLY-CLARK CORPORATION (US) | 1997-07-08 | — | — | US | disclosed |
| US-5643356-A | UNSATURATED KETONE SENSITIZER BONDED TO RADIATION TRANSORBER WITH COLOR, MOLECULAR INCLUDENT AND VEHICLES | KIMBERLY-CLARK CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5643701-A | Electrophotgraphic process utilizing mutable colored composition | KIMBERLY-CLARK CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1997020000-A2 | IMPROVED COLORANT STABILIZERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1997-06-05 | — | — | WO | disclosed |
| US-5616443-A | TONER FOR ELECTROGRAPHY | KIMBERLY-CLARK CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |
| WO-1997001605-A1 | NOVEL COLORANTS AND COLORANT MODIFIERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1997-01-16 | — | — | WO | disclosed |
| WO-1996039693-A1 | DIGITAL INFORMATION RECORDING MEDIA AND METHOD OF USING SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| WO-1996039467-A1 | IMPROVED INK FOR INK JET PRINTERS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| WO-1996019502-A1 | IMPROVED MUTABLE COMPOSITION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1996-06-27 | — | — | WO | disclosed |