SCHEMBL5698352

SCHEMBL5698352

OCCOc1cccc(C(CO)(CO)c2cccc(OCCO)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
RECQL P46063 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.42
SYK P43405 3/20 0.42
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PDK2 Q15119 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
PRSS1 P07477 2/20 0.39
ACSS2 Q9NR19 1/20 0.39
GAA P10253 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
MAOB P27338 1/20 0.38
AOC3 Q16853 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL99458 0.84 ALDH1A1 (0.52) ALDH1A1RECQLL3MBTL1SYKCYP3A4
SCHEMBL585718 0.84 L3MBTL1 (0.59) ALDH1A1RECQLL3MBTL1LMNAHTT
SCHEMBL29412242 0.84 ALDH1A1 (0.52) ALDH1A1RECQLL3MBTL1SYKCYP3A4
SCHEMBL13165245 0.84 L3MBTL1 (0.56) ALDH1A1RECQLL3MBTL1CYP3A4SMN1; SMN2
SCHEMBL48418 0.82 ALDH1A1 (0.70) ALDH1A1RECQLSYKKMT2APRSS1
Ethylene Glycol SCHEMBL7206927 0.80 ALDH1A1 (0.67) ALDH1A1RECQLSYKKMT2APRSS1
SCHEMBL5698350 0.78 ALDH1A1 (0.46) ALDH1A1RECQLL3MBTL1SYKCYP3A4
SCHEMBL19978961 0.78 KMT2A (0.49) ALDH1A1RECQLL3MBTL1CYP3A4SMN1; SMN2
SCHEMBL3715239 0.78 ALDH1A1 (0.64) ALDH1A1RECQLSYKPRSS1GAA
SCHEMBL17420767 0.77 ALDH1A1 (0.49) ALDH1A1RECQLL3MBTL1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486412-B2 Polyesters, polymer compositions, and methods of using thereof OHIO STATE INNOVATION FOUNDATION (US) 2025-12-02 US disclosed
EP-3870626-B1 POLYESTERS, POLYMER COMPOSITIONS, AND METHODS OF USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2023-07-12 EP disclosed
US-20210380826-A1 POLYESTERS, POLYMER COMPOSITIONS, AND METHODS OF USING THEREOF OHIO STATE INNOVATION FOUNDATION 2021-12-09 US disclosed
US-11130839-B2 Articles comprising isosorbide and processes for their manufacture EASTMAN CHEMICAL COMPANY (US) 2021-09-28 US disclosed
US-20190106535-A1 ARTICLES COMPRISING ISOSORBIDE AND PROCESSES FOR THEIR MANUFACTURE EASTMAN CHEMICAL COMPANY (US) 2019-04-11 US disclosed
US-20170073461-A1 ARTICLES COMPRISING ISOSORBIDE AND PROCESSES FOR THEIR MANUFACTURE EASTMAN CHEMICAL COMPANY (US) 2017-03-16 US disclosed
US-9517584-B2 Articles comprising isosorbide and processes for their manufacture EASTMAN CHEMICAL COMPANY (US) 2016-12-13 US disclosed
US-20150165668-A1 ARTICLES COMPRISING ISOSORBIDE AND PROCESSES FOR THEIR MANUFACTURE EASTMAN CHEMICAL COMPANY (US) 2015-06-18 US disclosed
EP-1560869-B1 METHOD FOR MAKING ISOSORBIDE CONTAINING POLYESTERS EASTMAN CHEM CO (US) 2006-07-26 EP disclosed
EP-1560869-A1 METHOD FOR MAKING ISOSORBIDE CONTAINING POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2005-08-10 EP disclosed
US-6914120-B2 Method for making isosorbide containing polyesters EASTMAN CHEMICAL COMPANY (US) 2005-07-05 US disclosed
WO-2004044032-A1 METHOD FOR MAKING ISOSORBIDE CONTAINING POLYESTERS EASTMAN CHEMICAL COMPANY (US) 2004-05-27 WO disclosed
US-20040092703-A1 Method for making isosorbide containing polyesters EASTMAN CHEMICAL COMPANY 2004-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486412-B2 Polyesters, polymer compositions, and methods of using thereof ACMSD, SORD, PGD ALDH1A1 523/4885RECQL 3764/4885L3MBTL1 2916/4885
US-20210380826-A1 POLYESTERS, POLYMER COMPOSITIONS, AND METHODS OF USING THEREOF ACMSD, SORD, PGD ALDH1A1 523/4885RECQL 3764/4885L3MBTL1 2916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.