Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bumetrizole SCHEMBL6068328 | 0.89 | NPC1 (0.60) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL1792777 | 0.87 | KCNMA1 (0.48) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL8054070 | 0.85 | NPC1 (0.53) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL29353083 | 0.85 | NPC1 (0.53) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL23734 | 0.85 | NPC1 (0.53) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL2398487 | 0.85 | NPC1 (0.53) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL8056551 | 0.85 | NPC1 (0.53) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL8603228 | 0.85 | NPC1 (0.53) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL9301984 | 0.84 | NPC1 (0.52) | NPC1RAB9APOLBLMNAATM | |
| Bumetrizole SCHEMBL9273939 | 0.84 | NPC1 (0.52) | NPC1RAB9APOLBLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866658-A | DISPERSED IN A CONTINUOUS OR CO-CONTINUOUS POLYAMIDE PHASE, MOLDED PARTS WHERE TOUGHNESS, HIGH GLOSS, ABRASION/SCRATCH (MAR) RESISTANCE, UV RESISTANCE, HIGH TEMPERATURE PROPERTIES AND STIFFNESS ARE DESIRED. | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-02 | — | — | US | disclosed |