Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698977 | 0.86 | RAB9A (0.41) | NPC1RAB9ACYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL4771783 | 0.84 | DNM1 (0.31) | DNM1ALDH1A1 | |
| SCHEMBL17202969 | 0.82 | DNM1 (0.31) | DNM1NPC1RAB9ACYP1A2ALDH1A1 | |
| SCHEMBL2771666 | 0.78 | MCHR1 (0.43) | CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL28347130 | 0.76 | RAD52 (0.37) | DNM1CYP1A2ALDH1A1RAD52 | |
| SCHEMBL83920 | 0.76 | RAD52 (0.44) | NPC1RAB9ACYP1A2ALDH1A1RAD52 | |
| SCHEMBL2860170 | 0.73 | CA12 (0.52) | RAB9AALDH1A1RAD52 | |
| SCHEMBL14940700 | 0.73 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL29710199 | 0.68 | CYP2C19 (0.45) | ALDH1A1L3MBTL1 | |
| SCHEMBL9320685 | 0.67 | ZDHHC20 (0.43) | CYP1A2ALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413289-B1 | Composition for oxidative dyeing of keratinous fibres containing a cationic polyvinyllactam and at least one C10-C14 fatty alcohol, and methods and kits for oxidative dyeing process | OREAL (FR) | 2008-07-23 | — | — | EP | claimed |
| US-20170042775-A1 | COSMETIC COMPOSITION | L'OREAL (FR) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170042775-A1 | COSMETIC COMPOSITION | CUTA, DSG1, H1-0 | DNM1 3221/4885NPC1 1514/4885RAB9A 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.