SCHEMBL5699189

SCHEMBL5699189

CC(C)CC(CN)c1ccc(C(CN)CC(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.39
GABBR2 O75899 9/20 0.38
GABBR1 Q9UBS5 9/20 0.38
LMNA P02545 3/20 0.38
CYP2C9 P11712 2/20 0.38
CYP1A2 P05177 2/20 0.38
THRB P10828 2/20 0.38
CYP3A4 P08684 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
NFKB1 P19838 1/20 0.38
DRD3 P35462 1/20 0.38
BLM P54132 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.37
PMP22 Q01453 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3647917 0.91 ACHE (0.39) TAAR1GABBR2GABBR1LMNACYP2C9
SCHEMBL21610467 0.89 GABBR2 (0.53) GABBR2GABBR1LMNACYP2C9CYP1A2
SCHEMBL3642655 0.89 GABBR2 (0.53) GABBR2GABBR1LMNACYP2C9CYP1A2
SCHEMBL19090082 0.89 TAAR1 (0.56) TAAR1GABBR2GABBR1
SCHEMBL2086299 0.89 TAAR1 (0.56) TAAR1GABBR2GABBR1
SCHEMBL19294780 0.89 TAAR1 (0.56) TAAR1GABBR2GABBR1
Hydrochloric Acid SCHEMBL3665299 0.88 GABBR2 (0.51) GABBR2GABBR1LMNACYP2C9CYP1A2
Hydrochloric Acid SCHEMBL3032167 0.87 TAAR1 (0.54) TAAR1GABBR2GABBR1
SCHEMBL17906493 0.86 CHRNB2 (0.55) TAAR1GABBR2GABBR1
SCHEMBL3748443 0.84 ALDH1A1 (0.46) TAAR1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1613604-B1 1-IMIDAZOLYLMETHYL-SUBSTITUTED-2-NAPHTOLS AND THEIR USE AS ACCELERATORS FOR LOW-TEMPERATURE CURING HUNTSMAN ADV MAT SWITZERLAND (CH) 2006-07-05 EP disclosed