Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681124 | 0.78 | TDP1 (0.47) | TDP1SMN1; SMN2NPC1MAPTMAPK1 | |
| SCHEMBL3644220 | 0.78 | CYP2C19 (0.43) | TDP1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL163160 | 0.78 | HTR3E (0.54) | TDP1SMN1; SMN2NPC1MAPTMAPK1 | |
| SCHEMBL834716 | 0.77 | NOS3 (0.48) | TDP1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL8799204 | 0.76 | MAPT (0.61) | TDP1SMN1; SMN2NPC1MAPTMAPK1 | |
| P-Xylene SCHEMBL28214560 | 0.76 | ALDH1A1 (0.50) | TDP1SMN1; SMN2NPC1MAPTMAPK1 | |
| SCHEMBL4770583 | 0.75 | SMN1; SMN2 (0.44) | TDP1SMN1; SMN2NPC1MAPTMAPK1 | |
| SCHEMBL3649880 | 0.75 | NOS3 (0.55) | SMN1; SMN2NPC1MAPTRAB9AHTR3E | |
| P-Xylene SCHEMBL5526703 | 0.74 | TDP1 (0.61) | TDP1SMN1; SMN2NPC1MAPTMAPK1 | |
| SCHEMBL10509447 | 0.73 | PLG (0.43) | SMN1; SMN2ALDH1A1CYP2D6CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1146037-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS | NIPPON SODA CO (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6410749-B1 | REACTING A CARBONYL COMPOUND WITH ORGANOMETALLIC COMPOUND | NIPPON SODA CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1146037-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS | NIPPON SODA CO., LTD. (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-4167511-A | ACTIVE HYDROGENS ON NITROGEN, OXYGEN AND SULFUR | DOW CORNING CORPORATION (US) | 1979-09-11 | — | — | US | disclosed |
| US-4104295-A | Methylsilacyclopentenyl-containing silylating agents and method therefor | DOW CORNING CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |