Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558112 | 0.89 | CHRNB2 (0.56) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL12835337 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL12173013 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL5582815 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL5858822 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL10685331 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL19918329 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL7296240 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL9268753 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL7300187 | 0.80 | ALOX15 (0.50) | ALDH1A1MAPTHPGDMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |