Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558112 | 0.86 | CHRNB2 (0.56) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL12835337 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL12173013 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL5582815 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL5700875 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL5858822 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL10685331 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL19918329 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL7296240 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 | |
| SCHEMBL5700803 | 0.79 | LMNA (0.53) | ALDH1A1MAPTHPGDCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666846-A4 | — | — | 1995-09-20 | — | — | EP | disclosed |
| EP-0666846-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO. INC. (US) | 1995-08-16 | — | — | EP | disclosed |