Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701034 | 0.81 | ALDH1A1 (0.58) | GAAFFAR1POLBSMN1; SMN2TDP1 | |
| SCHEMBL2386276 | 0.80 | GABBR2 (0.57) | GAAFFAR1POLBSMN1; SMN2TDP1 | |
| SCHEMBL5700957 | 0.74 | ALDH1A1 (0.64) | GAASMN1; SMN2LMNACYP2C9TSHR | |
| SCHEMBL5701026 | 0.74 | ALDH1A1 (0.51) | POLBSMN1; SMN2TDP1LMNACYP3A4 | |
| SCHEMBL4281827 | 0.72 | MAPT (0.43) | POLBSMN1; SMN2TDP1LMNACYP2C9 | |
| SCHEMBL28628025 | 0.71 | FFAR1 (0.59) | GAAFFAR1GABBR2GABBR1LMNA | |
| SCHEMBL16249736 | 0.71 | GABBR2 (0.61) | GAAFFAR1GABBR2GABBR1LMNA | |
| SCHEMBL4025536 | 0.70 | SLC22A6 (0.52) | SMN1; SMN2LMNAMAPT | |
| SCHEMBL5691981 | 0.70 | FFAR1 (0.59) | FFAR1POLBSMN1; SMN2TDP1GABBR2 | |
| SCHEMBL5691985 | 0.70 | FFAR1 (0.59) | FFAR1POLBSMN1; SMN2TDP1GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |