Biphenyl

Biphenyl

SCHEMBL5701245

O=C(Cl)c1ccc(-c2ccc(O)cc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
RAB9A P51151 2/20 0.64
LMNA P02545 1/20 0.64
MMP3 P08254 1/20 0.62
BCL2L1 Q07817 1/20 0.62
DEGS1 O15121 1/20 0.58
CES2 O00748 1/20 0.54
NPC1 O15118 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
EGFR P00533 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
HSD17B1 P14061 1/20 0.52
PDPK1 O15530 1/20 0.52
MIF P14174 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA3 P07451 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10635547 1.00 MAPT (0.64) MAPTMEN1KMT2ARAB9ALMNA
Biphenyl SCHEMBL28809192 0.91 SMN1; SMN2 (0.60) MAPTMEN1KMT2ARAB9ALMNA
SCHEMBL9452041 0.91 SMN1; SMN2 (0.60) MAPTMEN1KMT2ARAB9ALMNA
SCHEMBL8723556 0.91 SMN1; SMN2 (0.60) MAPTMEN1KMT2ARAB9ALMNA
SCHEMBL14416 0.91 SMN1; SMN2 (0.60) MAPTMEN1KMT2ARAB9ALMNA
Biphenyl SCHEMBL8775397 0.89 SMN1; SMN2 (0.58) MAPTMEN1KMT2ARAB9ALMNA
SCHEMBL22064857 0.85 EGFR (0.60) MAPTMEN1KMT2ARAB9ALMNA
Biphenyl SCHEMBL505047 0.84 RAB9A (0.52) MAPTMEN1KMT2ARAB9ALMNA
SCHEMBL1454951 0.84 LMNA (0.60) MAPTMEN1KMT2ARAB9ALMNA
Hydroquinone SCHEMBL7948998 0.84 LMNA (0.60) MAPTMEN1KMT2ARAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1143048-B1 PROCESS FOR PRODUCING META-AROMATIC POLYAMIDE FIBER TEIJIN LTD (JP) 2006-06-28 EP disclosed
US-6569987-B1 Polymerization, neutralization, spinning, coagulation, drawing, heat treatment TEIJIN LIMITED (JP) 2003-05-27 US disclosed
EP-1143048-A1 PROCESS FOR PRODUCING META-AROMATIC POLYAMIDE FIBER TEIJIN LIMITED (JP) 2001-10-10 EP disclosed