SCHEMBL14416

SCHEMBL14416

O=C(Cl)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 4/20 0.60
RAB9A P51151 3/20 0.56
NPC1 O15118 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.54
PTPN1 P18031 2/20 0.54
GSK3B P49841 1/20 0.54
LMNA P02545 3/20 0.52
CDC25B P30305 1/20 0.52
ATM Q13315 1/20 0.52
FFAR1 O14842 1/20 0.52
CYP1A2 P05177 1/20 0.52
HIF1A Q16665 1/20 0.52
HPGD P15428 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
HAO1 Q9UJM8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9452041 1.00 SMN1; SMN2 (0.60) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
Biphenyl SCHEMBL28809192 1.00 SMN1; SMN2 (0.60) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL8723556 1.00 SMN1; SMN2 (0.60) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
Biphenyl SCHEMBL8775397 0.98 SMN1; SMN2 (0.58) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL22064857 0.93 EGFR (0.60) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
Biphenyl SCHEMBL505047 0.92 RAB9A (0.52) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
Biphenyl SCHEMBL5701245 0.91 MAPT (0.64) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL10635547 0.91 MAPT (0.64) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL10670934 0.89 ALDH1A1 (0.52) SMN1; SMN2MAPTRAB9ANPC1CTDSP1
SCHEMBL727046 0.89 ALDH1A1 (0.52) SMN1; SMN2MAPTRAB9ANPC1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2034 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080343-A Method for synthesizing polyarylketone compound 2026-05-26 CN claimed
US-20250249410-A1 HIGHLY SELECTIVE ACID-RESISTANT POLYAMIDE NANOFILTRATION MEMBRANE CONTAINING TROGER'S BASE AND PREPARATION METHOD THEREOF ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2025-08-07 US claimed
CN-119431424-A Silicon oxime ester-containing photoinitiator, preparation method and application thereof 常州强力先端电子材料有限公司 2025-02-14 CN claimed
CN-119409969-A Benzimidazole transparent polyimide film and preparation method and application thereof 东华大学 2025-02-11 CN claimed
CN-119345914-A Super-crosslinked microporous polymer composite membrane and preparation method thereof 四川大学 2025-01-24 CN claimed
WO-2024250573-A1 REVERSE OSMOSIS MEMBRANE PREPARATION METHOD AND REVERSE OSMOSIS MEMBRANE PREPARED THEREBY 沃顿科技股份有限公司 2024-12-12 WO claimed
CN-119098067-A Method for producing reverse osmosis membrane and reverse osmosis membrane produced thereby 沃顿科技股份有限公司 2024-12-10 CN claimed
CN-112851547-B Fluorene oxime ester compound, preparation method thereof and photosensitive resin composition 常州强力先端电子材料有限公司 2024-06-07 CN claimed
CN-117986231-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-113387864-B S-indole benzamide derivative and preparation method and application thereof 广西大学 2023-08-01 CN claimed
CN-101437524-A Preparation of 2 '-fluoro-2' -alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and derivatives thereof PHARMASSET INC (US) 2009-05-20 CN claimed
EP-1809301-A2 PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES Pharmasset, Inc. (US) 2007-07-25 EP claimed
US-20060122146-A1 Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives GILEAD SCIENCES, INC. 2006-06-08 US claimed
WO-2006031725-A2 PREPARATION OF 2'­FLUORO-2'- ALKYL- SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES PHARMASSET, INC. (US) 2006-03-23 WO claimed
EP-0899266-B1 Process for the production of benzoxazinones CIBA SC HOLDING AG (CH) 2003-01-15 EP claimed
US-6040443-A Process for the production of benzoxazinones CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-03-21 US claimed
EP-0899266-A1 Process for the production of benzoxazinones Ciba SC Holding AG (CH) 1999-03-03 EP claimed
US-4398020-A FROM ACYL HALIDES AND HYDROCARBONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-09 US claimed
EP-0063874-A1 Production of aromatic polyketones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-11-03 EP claimed
US-4176122-A Process for the preparation of bicyclic enone compounds CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK (HU) 1979-11-27 US claimed