Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576617 | 0.86 | — | — | |
| SCHEMBL5747297 | 0.80 | KIF11 (0.39) | PDE2A | |
| SCHEMBL5746326 | 0.75 | MRGPRX4 (0.36) | MRGPRX4PDE2AMAPTACACBALDH1A1 | |
| SCHEMBL5747293 | 0.74 | MAPT (0.40) | MRGPRX4PDE2AMAPTMEN1KMT2A | |
| SCHEMBL5747289 | 0.74 | PDE2A (0.35) | MRGPRX4PDE2AMAPTMEN1KMT2A | |
| SCHEMBL3326974 | 0.69 | RAPGEF3 (0.34) | MRGPRX4MAPTMEN1KMT2AHPGD | |
| SCHEMBL9811175 | 0.68 | PDE2A (0.36) | MRGPRX4PDE2AMAPTL3MBTL1ACACB | |
| SCHEMBL5744940 | 0.67 | MRGPRX4 (0.37) | MRGPRX4PDE2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5743667 | 0.65 | ALDH1A1 (0.34) | MRGPRX4PDE2AMAPTALDH1A1HTT | |
| SCHEMBL10954291 | 0.63 | ALDH1A1 (0.39) | MRGPRX4PDE2AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1378506-B1 | Process for the preparation of phenyl pyrazole compounds | BASF AGRO B V ARNHEM NL WAEDEN (CH) | 2006-07-26 | — | — | EP | claimed |
| WO-2004005245-A1 | PROCESS FOR THE PREPARATION OF PHENYL PYRAZOLE COMPOUNDS | BASF AGRO B.V. ARNHEM (NL) (CH) | 2004-01-15 | — | — | WO | claimed |
| EP-1378506-A1 | Process for the preparation of phenyl pyrazole compounds | Bayer CropScience S.A. (FR) | 2004-01-07 | — | — | EP | claimed |
| US-6258973-B1 | OXIDATION | RHONE-POULENC AGRO (FR) | 2001-07-10 | — | — | US | claimed |
| US-7094906-B2 | Processes for preparing pesticidal intermediates | Basf Agro B.V. Arnthem (NL) Wädenswil-Branch (CH) | 2006-08-22 | — | — | US | disclosed |
| EP-1378506-B1 | Process for the preparation of phenyl pyrazole compounds | BASF AGRO B V ARNHEM NL WAEDEN (CH) | 2006-07-26 | — | — | EP | disclosed |
| EP-0952145-B1 | Process for preparing pesticidal intermediates | BASF AGRO BV (CH) | 2005-10-05 | — | — | EP | disclosed |
| EP-1073627-B1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | BAYER AGRICULTURE LTD (GB) | 2004-12-01 | — | — | EP | disclosed |
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | AVENTIS AGRICULTURE LTD. (GB) | 2004-10-07 | — | — | US | disclosed |
| WO-2004005245-A1 | PROCESS FOR THE PREPARATION OF PHENYL PYRAZOLE COMPOUNDS | BASF AGRO B.V. ARNHEM (NL) (CH) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378506-A1 | Process for the preparation of phenyl pyrazole compounds | Bayer CropScience S.A. (FR) | 2004-01-07 | — | — | EP | disclosed |
| US-6673956-B2 | INTERMEDIATES (PARTICULARLY 2-(ARYLHYDRAZINO)SUCCINONITRILE COMPOUNDS AND 3-(ARYLHYDRAZONO)PROPIONITRILE DERIVATIVES FOR PESTICIDES, BY REACTING DIALKOXYPROPIONITRILE WITH AN ACID ADDITION SALT OF ARYLHYDRAZINE | AVENTIS AGRICULTURE LTD. (GB) | 2004-01-06 | — | — | US | disclosed |
| US-6258973-B1 | OXIDATION | RHONE-POULENC AGRO (FR) | 2001-07-10 | — | — | US | disclosed |
| EP-1073627-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 2001-02-07 | — | — | EP | disclosed |
| US-6084105-A | Processes for preparing pesticidal intermediates | RHONE-POULENC AGRO (FR) | 2000-07-04 | — | — | US | disclosed |
| EP-0966445-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | RHONE-POULENC AGRO (FR) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999054288-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 1999-10-28 | — | — | WO | disclosed |
| EP-0952145-A1 | Process for preparing pesticidal intermediates | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-10-27 | — | — | EP | disclosed |
| EP-0952144-A1 | Processes for preparing pesticidal intermediates | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998039302-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | RHONE-POULENC AGRO (FR) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | SFXN3, SFXN1, CYP4F3 | MRGPRX4 1266/4885PDE2A 1250/4885MAPT 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.