Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701320 | 0.75 | MRGPRX4 (0.34) | MRGPRX4ALDH1A1HTTSMN1; SMN2PDE2A | |
| SCHEMBL5746321 | 0.70 | GAA (0.34) | MRGPRX4ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL5744940 | 0.69 | MRGPRX4 (0.37) | MRGPRX4ALDH1A1HTTSMN1; SMN2PDE2A | |
| SCHEMBL5795159 | 0.69 | TRPV4 (0.52) | MRGPRX4 | |
| Hydrochloric Acid SCHEMBL6578636 | 0.68 | GAA (0.33) | MRGPRX4KDM4E | |
| SCHEMBL5743667 | 0.68 | ALDH1A1 (0.34) | MRGPRX4ALDH1A1HTTSMN1; SMN2PDE2A | |
| SCHEMBL5747289 | 0.67 | PDE2A (0.35) | MRGPRX4ALDH1A1HTTSMN1; SMN2PDE2A | |
| SCHEMBL9145901 | 0.66 | MRGPRX4 (0.59) | MRGPRX4 | |
| SCHEMBL1768930 | 0.66 | PDE2A (0.49) | MRGPRX4ALDH1A1HTTPDE2ANR1H2 | |
| SCHEMBL4961852 | 0.65 | MRGPRX4 (0.47) | MRGPRX4ALDH1A1HTTSMN1; SMN2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094906-B2 | Processes for preparing pesticidal intermediates | Basf Agro B.V. Arnthem (NL) Wädenswil-Branch (CH) | 2006-08-22 | — | — | US | disclosed |
| EP-0952145-B1 | Process for preparing pesticidal intermediates | BASF AGRO BV (CH) | 2005-10-05 | — | — | EP | disclosed |
| EP-1073627-B1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | BAYER AGRICULTURE LTD (GB) | 2004-12-01 | — | — | EP | disclosed |
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | AVENTIS AGRICULTURE LTD. (GB) | 2004-10-07 | — | — | US | disclosed |
| US-6673956-B2 | INTERMEDIATES (PARTICULARLY 2-(ARYLHYDRAZINO)SUCCINONITRILE COMPOUNDS AND 3-(ARYLHYDRAZONO)PROPIONITRILE DERIVATIVES FOR PESTICIDES, BY REACTING DIALKOXYPROPIONITRILE WITH AN ACID ADDITION SALT OF ARYLHYDRAZINE | AVENTIS AGRICULTURE LTD. (GB) | 2004-01-06 | — | — | US | disclosed |
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | MERIAL LIMITED | 2002-09-12 | — | — | US | disclosed |
| US-6392081-B1 | REACTING A NITRILE COMPOUND CONTAINING ACTAL GROUPS WITH ARYLHYDRAZINE; OXIDATION | AVENTIS AGRICULTURE LTD. (GB) | 2002-05-21 | — | — | US | disclosed |
| EP-1073627-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054288-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 1999-10-28 | — | — | WO | disclosed |
| EP-0952145-A1 | Process for preparing pesticidal intermediates | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | SFXN3, SFXN1, CYP4F3 | MRGPRX4 1266/4885ALDH1A1 3068/4885HTT 3819/4885 |
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | CBR3, HCN1, SF3A3 | MRGPRX4 1583/4885ALDH1A1 2835/4885HTT 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.