Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896028 | 0.83 | NCEH1 (0.41) | NCEH1MAPTMEN1KMT2AGAA | |
| SCHEMBL6513683 | 0.74 | HPGD (0.42) | NCEH1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6513679 | 0.74 | HPGD (0.42) | NCEH1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28918790 | 0.70 | NCEH1 (0.32) | NCEH1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL48068 | 0.68 | CYP19A1 (0.49) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL48069 | 0.68 | CYP19A1 (0.49) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL6706294 | 0.67 | ALDH1A1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL9782844 | 0.67 | PTGS2 (0.39) | NCEH1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27697199 | 0.66 | PKM (0.47) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL1551750 | 0.65 | POLB (0.46) | MAPTKMT2AGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701744-A2 | THIOL-CLEAVABLE LINKAGE BETWEEN POLYMER AND LIGAND | ALZA CORPORATION (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005053749-A2 | THIOL-CLEAVABLE LINKAGE BETWEEN POLYMER AND LIGAND | ALZA CORPORATION (US) | 2005-06-16 | — | — | WO | disclosed |